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pH-Sensing G Protein-Coupled Receptor OGR1 (GPR68) Expression and Activation Increases in Intestinal Inflammation and Fibrosis

Local extracellular acidification occurs at sites of inflammation. Proton-sensing ovarian cancer G-protein-coupled receptor 1 (OGR1, also known as GPR68) responds to decreases in extracellular pH. Our previous studies show a role for OGR1 in the pathogenesis of mucosal inflammation, suggesting a lin...

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Detalles Bibliográficos
Autores principales:	de Vallière, Cheryl, Cosin-Roger, Jesus, Baebler, Katharina, Schoepflin, Anja, Mamie, Céline, Mollet, Michelle, Schuler, Cordelia, Bengs, Susan, Lang, Silvia, Scharl, Michael, Seuwen, Klaus, Ruiz, Pedro A., Hausmann, Martin, Rogler, Gerhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835966/ https://www.ncbi.nlm.nih.gov/pubmed/35163345 http://dx.doi.org/10.3390/ijms23031419

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