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Thyroid Hormone Receptor α Controls the Hind Limb Metamorphosis by Regulating Cell Proliferation and Wnt Signaling Pathways in Xenopus tropicalis

Thyroid hormone (T3) receptors (TRs) mediate T3 effects on vertebrate development. We have studied Xenopus tropicalis metamorphosis as a model for postembryonic human development and demonstrated that TRα knockout induces precocious hind limb development. To reveal the molecular pathways regulated b...

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Detalles Bibliográficos
Autores principales: Tanizaki, Yuta, Shibata, Yuki, Zhang, Hongen, Shi, Yun-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835992/
https://www.ncbi.nlm.nih.gov/pubmed/35163147
http://dx.doi.org/10.3390/ijms23031223