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Bioactive Peptides: Synthesis, Sources, Applications, and Proposed Mechanisms of Action
Bioactive peptides are a group of biological molecules that are normally buried in the structure of parent proteins and become active after the cleavage of the proteins. Another group of peptides is actively produced and found in many microorganisms and the body of organisms. Today, many groups of b...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836030/ https://www.ncbi.nlm.nih.gov/pubmed/35163367 http://dx.doi.org/10.3390/ijms23031445 |
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author | Akbarian, Mohsen Khani, Ali Eghbalpour, Sara Uversky, Vladimir N. |
author_facet | Akbarian, Mohsen Khani, Ali Eghbalpour, Sara Uversky, Vladimir N. |
author_sort | Akbarian, Mohsen |
collection | PubMed |
description | Bioactive peptides are a group of biological molecules that are normally buried in the structure of parent proteins and become active after the cleavage of the proteins. Another group of peptides is actively produced and found in many microorganisms and the body of organisms. Today, many groups of bioactive peptides have been marketed chemically or recombinantly. This article reviews the various production methods and sources of these important/ubiquitous and useful biomolecules. Their applications, such as antimicrobial, antihypertensive, antioxidant activities, blood-lipid-lowering effect, opioid role, antiobesity, ability to bind minerals, antidiabetic, and antiaging effects, will be explored. The types of pathways proposed for bioactive applications will be in the next part of the article, and at the end, the future perspectives of bioactive peptides will be reviewed. Reading this article is recommended for researchers interested in various fields of physiology, microbiology, biochemistry, and nanotechnology and food industry professionals. |
format | Online Article Text |
id | pubmed-8836030 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-88360302022-02-12 Bioactive Peptides: Synthesis, Sources, Applications, and Proposed Mechanisms of Action Akbarian, Mohsen Khani, Ali Eghbalpour, Sara Uversky, Vladimir N. Int J Mol Sci Review Bioactive peptides are a group of biological molecules that are normally buried in the structure of parent proteins and become active after the cleavage of the proteins. Another group of peptides is actively produced and found in many microorganisms and the body of organisms. Today, many groups of bioactive peptides have been marketed chemically or recombinantly. This article reviews the various production methods and sources of these important/ubiquitous and useful biomolecules. Their applications, such as antimicrobial, antihypertensive, antioxidant activities, blood-lipid-lowering effect, opioid role, antiobesity, ability to bind minerals, antidiabetic, and antiaging effects, will be explored. The types of pathways proposed for bioactive applications will be in the next part of the article, and at the end, the future perspectives of bioactive peptides will be reviewed. Reading this article is recommended for researchers interested in various fields of physiology, microbiology, biochemistry, and nanotechnology and food industry professionals. MDPI 2022-01-27 /pmc/articles/PMC8836030/ /pubmed/35163367 http://dx.doi.org/10.3390/ijms23031445 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Akbarian, Mohsen Khani, Ali Eghbalpour, Sara Uversky, Vladimir N. Bioactive Peptides: Synthesis, Sources, Applications, and Proposed Mechanisms of Action |
title | Bioactive Peptides: Synthesis, Sources, Applications, and Proposed Mechanisms of Action |
title_full | Bioactive Peptides: Synthesis, Sources, Applications, and Proposed Mechanisms of Action |
title_fullStr | Bioactive Peptides: Synthesis, Sources, Applications, and Proposed Mechanisms of Action |
title_full_unstemmed | Bioactive Peptides: Synthesis, Sources, Applications, and Proposed Mechanisms of Action |
title_short | Bioactive Peptides: Synthesis, Sources, Applications, and Proposed Mechanisms of Action |
title_sort | bioactive peptides: synthesis, sources, applications, and proposed mechanisms of action |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836030/ https://www.ncbi.nlm.nih.gov/pubmed/35163367 http://dx.doi.org/10.3390/ijms23031445 |
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