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Bioactive Peptides: Synthesis, Sources, Applications, and Proposed Mechanisms of Action

Bioactive peptides are a group of biological molecules that are normally buried in the structure of parent proteins and become active after the cleavage of the proteins. Another group of peptides is actively produced and found in many microorganisms and the body of organisms. Today, many groups of b...

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Detalles Bibliográficos
Autores principales: Akbarian, Mohsen, Khani, Ali, Eghbalpour, Sara, Uversky, Vladimir N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836030/
https://www.ncbi.nlm.nih.gov/pubmed/35163367
http://dx.doi.org/10.3390/ijms23031445
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author Akbarian, Mohsen
Khani, Ali
Eghbalpour, Sara
Uversky, Vladimir N.
author_facet Akbarian, Mohsen
Khani, Ali
Eghbalpour, Sara
Uversky, Vladimir N.
author_sort Akbarian, Mohsen
collection PubMed
description Bioactive peptides are a group of biological molecules that are normally buried in the structure of parent proteins and become active after the cleavage of the proteins. Another group of peptides is actively produced and found in many microorganisms and the body of organisms. Today, many groups of bioactive peptides have been marketed chemically or recombinantly. This article reviews the various production methods and sources of these important/ubiquitous and useful biomolecules. Their applications, such as antimicrobial, antihypertensive, antioxidant activities, blood-lipid-lowering effect, opioid role, antiobesity, ability to bind minerals, antidiabetic, and antiaging effects, will be explored. The types of pathways proposed for bioactive applications will be in the next part of the article, and at the end, the future perspectives of bioactive peptides will be reviewed. Reading this article is recommended for researchers interested in various fields of physiology, microbiology, biochemistry, and nanotechnology and food industry professionals.
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spelling pubmed-88360302022-02-12 Bioactive Peptides: Synthesis, Sources, Applications, and Proposed Mechanisms of Action Akbarian, Mohsen Khani, Ali Eghbalpour, Sara Uversky, Vladimir N. Int J Mol Sci Review Bioactive peptides are a group of biological molecules that are normally buried in the structure of parent proteins and become active after the cleavage of the proteins. Another group of peptides is actively produced and found in many microorganisms and the body of organisms. Today, many groups of bioactive peptides have been marketed chemically or recombinantly. This article reviews the various production methods and sources of these important/ubiquitous and useful biomolecules. Their applications, such as antimicrobial, antihypertensive, antioxidant activities, blood-lipid-lowering effect, opioid role, antiobesity, ability to bind minerals, antidiabetic, and antiaging effects, will be explored. The types of pathways proposed for bioactive applications will be in the next part of the article, and at the end, the future perspectives of bioactive peptides will be reviewed. Reading this article is recommended for researchers interested in various fields of physiology, microbiology, biochemistry, and nanotechnology and food industry professionals. MDPI 2022-01-27 /pmc/articles/PMC8836030/ /pubmed/35163367 http://dx.doi.org/10.3390/ijms23031445 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Akbarian, Mohsen
Khani, Ali
Eghbalpour, Sara
Uversky, Vladimir N.
Bioactive Peptides: Synthesis, Sources, Applications, and Proposed Mechanisms of Action
title Bioactive Peptides: Synthesis, Sources, Applications, and Proposed Mechanisms of Action
title_full Bioactive Peptides: Synthesis, Sources, Applications, and Proposed Mechanisms of Action
title_fullStr Bioactive Peptides: Synthesis, Sources, Applications, and Proposed Mechanisms of Action
title_full_unstemmed Bioactive Peptides: Synthesis, Sources, Applications, and Proposed Mechanisms of Action
title_short Bioactive Peptides: Synthesis, Sources, Applications, and Proposed Mechanisms of Action
title_sort bioactive peptides: synthesis, sources, applications, and proposed mechanisms of action
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836030/
https://www.ncbi.nlm.nih.gov/pubmed/35163367
http://dx.doi.org/10.3390/ijms23031445
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