9-Aminoacridine Inhibits Ribosome Biogenesis by Targeting Both Transcription and Processing of Ribosomal RNA

Aminoacridines, used for decades as antiseptic and antiparasitic agents, are prospective candidates for therapeutic repurposing and new drug development. Although the mechanisms behind their biological effects are not fully elucidated, they are most often attributed to the acridines’ ability to inte...

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Detalles Bibliográficos
Autores principales: Anikin, Leonid, Pestov, Dimitri G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836032/
https://www.ncbi.nlm.nih.gov/pubmed/35163183
http://dx.doi.org/10.3390/ijms23031260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836032/
https://www.ncbi.nlm.nih.gov/pubmed/35163183
http://dx.doi.org/10.3390/ijms23031260

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