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A Polymorphism of Bactericidal/Permeability-Increasing Protein Affects Its Neutralization Efficiency towards Lipopolysaccharide

Gram-negative sepsis driven by lipopolysaccharide (LPS) has detrimental outcomes, especially in neonates. The neutrophil-derived bactericidal/permeability-increasing protein (BPI) potently neutralizes LPS. Interestingly, polymorphism of the BPI gene at position 645 (rs4358188) corresponds to a favor...

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Detalles Bibliográficos
Autores principales:	Ederer, Katharina U., Holzinger, Jonas M., Maier, Katharina T., Zeller, Lisa, Werner, Maren, Toelge, Martina, Gessner, André, Bülow, Sigrid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836039/ https://www.ncbi.nlm.nih.gov/pubmed/35163248 http://dx.doi.org/10.3390/ijms23031324

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