Cargando…

Identification of a Novel Theranostic Signature of Metabolic and Immune-Inflammatory Dysregulation in Myocardial Infarction, and the Potential Therapeutic Properties of Ovatodiolide, a Diterpenoid Derivative

Myocardial infarction (MI) is a multifactorial global disease, recognized as one of the leading causes of cardiovascular morbidity and mortality. Timely and correct diagnoses and effective treatments could significantly reduce incidence of complications and improve patient prognoses. In this study,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Alexander T. H., Lawal, Bashir, Tzeng, Yew-Min, Shih, Chun-Che, Shih, Chun-Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836044/ https://www.ncbi.nlm.nih.gov/pubmed/35163208 http://dx.doi.org/10.3390/ijms23031281

Ejemplares similares

Genotoxicity and 28-day repeated dose oral toxicity study of ovatodiolide in rats
por: Chen, Jing-Chun, et al.
Publicado: (2021)

Identification of Cancer Hub Gene Signatures Associated with Immune-Suppressive Tumor Microenvironment and Ovatodiolide as a Potential Cancer Immunotherapeutic Agent
por: Chen, Jia-Hong, et al.
Publicado: (2021)

Ovatodiolide Inhibits Breast Cancer Stem/Progenitor Cells through SMURF2-Mediated Downregulation of Hsp27
por: Lu, Kuan-Ta, et al.
Publicado: (2016)

Antioxidative Characteristics of Anisomeles indica Extract and Inhibitory Effect of Ovatodiolide on Melanogenesis
por: Huang, Huey-Chun, et al.
Publicado: (2012)

Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways
por: Huang, Yan-Jiun, et al.
Publicado: (2017)

Ovatodiolide of Anisomeles indica Exerts the Anticancer Potential on Pancreatic Cancer Cell Lines through STAT3 and NF-κB Regulation
por: Hsieh, Ya-Ju, et al.
Publicado: (2016)

Ovatodiolide Suppresses Oral Cancer Malignancy by Down-Regulating Exosomal Mir-21/STAT3/β-Catenin Cargo and Preventing Oncogenic Transformation of Normal Gingival Fibroblasts
por: Chen, Jia-Hong, et al.
Publicado: (2019)

Antibacterial activity of ovatodiolide isolated from Anisomeles indica against Helicobacter pylori
por: Lien, Hsiu-Man, et al.
Publicado: (2019)

Nitrogen-Containing Diterpenoids, Sesquiterpenoids, and Nor-Diterpenoids from Cespitularia taeniata
por: Wang, Shih-Sheng, et al.
Publicado: (2015)

Ovatodiolide Targets β-Catenin Signaling in Suppressing Tumorigenesis and Overcoming Drug Resistance in Renal Cell Carcinoma
por: Ho, Jar-Yi, et al.
Publicado: (2013)

Innovative Purification Method of Ovatodiolide from Anisomeles indica to Induce Apoptosis in Human Gastric Cancer Cells
por: Lien, Hsiu-Man, et al.
Publicado: (2022)

Multiparametric Immunoimaging Maps Inflammatory Signatures in Murine Myocardial Infarction Models
por: Maier, Alexander, et al.
Publicado: (2023)

Transcriptomic Profiling Unravels Novel Deregulated Gene Signatures Associated with Acute Myocardial Infarction: A Bioinformatics Approach
por: Kumar, Sanjay, et al.
Publicado: (2022)

Marine Diterpenoids as Potential Anti-Inflammatory Agents
por: González, Yisett, et al.
Publicado: (2015)

Plasmonic Gold Nanoisland Film for Bacterial Theranostics
por: Tan, Shih-Hua, et al.
Publicado: (2021)

Diterpenoids from the Roots of Salvia yunnanensis
por: Xia, Fan, et al.
Publicado: (2015)

Nanoparticles for diagnosis and therapy of atherosclerosis and myocardial infarction: evolution toward prospective theranostic approaches
por: Bejarano, Julian, et al.
Publicado: (2018)

Ovatodiolide targets chronic myeloid leukemia stem cells by epigenetically upregulating hsa-miR-155, suppressing the BCR-ABL fusion gene and dysregulating the PI3K/AKT/mTOR pathway
por: Tu, Yue-Xing, et al.
Publicado: (2017)

The drug likeness analysis of anti-inflammatory clerodane diterpenoids
por: Feng, Zheling, et al.
Publicado: (2020)

Diterpenoids from Blumea balsamifera and Their Anti-Inflammatory Activities
por: Huang, Xiao-Ling, et al.
Publicado: (2022)

Multifunctional Cyanine-Based Theranostic Probe for Cancer Imaging and Therapy
por: Peng, Cheng-Liang, et al.
Publicado: (2021)

Post-myocardial infarction heart failure dysregulates the bone vascular niche
por: Hoffmann, Jedrzej, et al.
Publicado: (2021)

The analytical and biomedical applications of carbon dots and their future theranostic potential: A review
por: Ross, Sukunya, et al.
Publicado: (2020)

Diterpenoids with Anti-Inflammatory Activity from the Wood of Cunninghamia konishii
por: Chen, Yu-Chang, et al.
Publicado: (2013)

Clerodane Diterpenoids from Callicarpa hypoleucophylla and Their Anti-Inflammatory Activity
por: Lin, Yu-Chi, et al.
Publicado: (2020)

Dual-targeting Theranostic System with Mimicking Apoptosis to Promote Myocardial Infarction Repair via Modulation of Macrophages
por: Chen, Jingli, et al.
Publicado: (2017)

Briarane Diterpenoids from the Gorgonian Dichotella gemmacea
por: La, Ming-Ping, et al.
Publicado: (2014)

PSMA Theranostics: Science and Practice
por: Mokoala, Kgomotso, et al.
Publicado: (2021)

Effects of renal impairment on cardiac remodeling and clinical outcomes after myocardial infarction
por: Chiang, Chun-Yen, et al.
Publicado: (2021)

Ovatodiolide inhibits SARS-CoV-2 replication and ameliorates pulmonary fibrosis through suppression of the TGF-β/TβRs signaling pathway
por: Chiou, Wei-Chung, et al.
Publicado: (2023)

Novel Diterpenoids from the Twigs of Podocarpus nagi
por: Zheng, Yuan-Dong, et al.
Publicado: (2016)

ent-Kaurane diterpenoids from the plant Wedelia trilobata
por: Ma, Bing-Ji, et al.
Publicado: (2013)

Stemarane Diterpenes and Diterpenoids †
por: Leonelli, Francesca, et al.
Publicado: (2019)

Therapeutics That Promote Sympathetic Reinnervation Modulate the Inflammatory Response After Myocardial Infarction
por: Sepe, Joseph J., et al.
Publicado: (2022)

Discovery of Novel Diterpenoids from Sinularia arborea
por: Chen, Kuan-Hua, et al.
Publicado: (2014)

Antifeedant and Antiviral Diterpenoids from the Fresh Roots of Euphorbia jolkinii
por: Huang, Chun-Shuai, et al.
Publicado: (2014)

Wnt signaling pathways in myocardial infarction and the therapeutic effects of Wnt pathway inhibitors
por: Fu, Wen-bin, et al.
Publicado: (2018)

Dysregulated lncRNAs are involved in the progress of myocardial infarction by constructing regulatory networks
por: Yang, Jingqi, et al.
Publicado: (2023)

Identification of a novel immune-inflammatory signature of COVID-19 infections, and evaluation of pharmacokinetics and therapeutic potential of RXn-02, a novel small-molecule derivative of quinolone
por: Lawal, Bashir, et al.
Publicado: (2022)

New Antifeedant Grayanane Diterpenoids from the Flowers of Pieris formosa
por: Li, Chun-Huan, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_8phuvpahlelcqqdr8su75jj8sc