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The Transmembrane Protease TMPRSS2 as a Therapeutic Target for COVID-19 Treatment

TMPRSS2 is a type II transmembrane protease with broad expression in epithelial cells of the respiratory and gastrointestinal tract, the prostate, and other organs. Although the physiological role of TMPRSS2 remains largely elusive, several endogenous substrates have been identified. TMPRSS2 serves...

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Detalles Bibliográficos
Autores principales: Wettstein, Lukas, Kirchhoff, Frank, Münch, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836196/
https://www.ncbi.nlm.nih.gov/pubmed/35163273
http://dx.doi.org/10.3390/ijms23031351