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High Iron and Iron Household Protein Contents in Perineuronal Net-Ensheathed Neurons Ensure Energy Metabolism with Safe Iron Handling

A subpopulation of neurons is less vulnerable against iron-induced oxidative stress and neurodegeneration. A key feature of these neurons is a special extracellular matrix composition that forms a perineuronal net (PN). The PN has a high affinity to iron, which suggests an adapted iron sequestration...

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Detalles Bibliográficos
Autores principales: Reinert, Anja, Reinert, Tilo, Arendt, Thomas, Morawski, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836250/
https://www.ncbi.nlm.nih.gov/pubmed/35163558
http://dx.doi.org/10.3390/ijms23031634