Protein Biochemistry and Molecular Modeling of the Intra-Melanosomal Domain of Human Recombinant Tyrp2 Protein and OCA8-Related Mutant Variants

Tyrosinase-related protein 2 (Tyrp2) is involved in the melanogenesis pathway, catalyzing the tautomerization of dopachrome to 5,6-dihydroxyindole-2-carboxylic acid (DHICA). Recently, a new type of albinism was discovered with disease-causing mutations in the TYRP2 gene. Here, for the first time, we...

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Detalles Bibliográficos
Autores principales: Dolinska, Monika B., Woods, Taariq, Osuna, Isabella, Sergeev, Yuri V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836267/
https://www.ncbi.nlm.nih.gov/pubmed/35163231
http://dx.doi.org/10.3390/ijms23031305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836267/
https://www.ncbi.nlm.nih.gov/pubmed/35163231
http://dx.doi.org/10.3390/ijms23031305

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