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Unravelling Mechanisms of Doxorubicin-Induced Toxicity in 3D Human Intestinal Organoids

Doxorubicin is widely used in the treatment of different cancers, and its side effects can be severe in many tissues, including the intestines. Symptoms such as diarrhoea and abdominal pain caused by intestinal inflammation lead to the interruption of chemotherapy. Nevertheless, the molecular mechan...

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Detalles Bibliográficos
Autores principales: Rodrigues, Daniela, Coyle, Luke, Füzi, Barbara, Ferreira, Sofia, Jo, Heeseung, Herpers, Bram, Chung, Seung-Wook, Fisher, Ciarán, Kleinjans, Jos C. S., Jennen, Danyel, de Kok, Theo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836276/
https://www.ncbi.nlm.nih.gov/pubmed/35163210
http://dx.doi.org/10.3390/ijms23031286