Characterization of adenine phosphoribosyltransferase (APRT) activity in Trypanosoma brucei brucei: Only one of the two isoforms is kinetically active

Human African Trypanosomiasis (HAT), also known as sleeping sickness, is a Neglected Tropical Disease endemic to 36 African countries, with approximately 70 million people currently at risk for infection. Current therapeutics are suboptimal due to toxicity, adverse side effects, and emerging resista...

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Detalles Bibliográficos
Autores principales: Glockzin, Kayla, Meek, Thomas D., Katzfuss, Ardala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836349/
https://www.ncbi.nlm.nih.gov/pubmed/35104286
http://dx.doi.org/10.1371/journal.pntd.0009926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836349/
https://www.ncbi.nlm.nih.gov/pubmed/35104286
http://dx.doi.org/10.1371/journal.pntd.0009926

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