Cargando…
High, in Contrast to Low Levels of Acute Stress Induce Depressive-like Behavior by Involving Astrocytic, in Addition to Microglial P2X7 Receptors in the Rodent Hippocampus
Extracellular adenosine 5′-triphosphate (ATP) in the brain is suggested to be an etiological factor of major depressive disorder (MDD). It has been assumed that stress-released ATP stimulates P2X7 receptors (Rs) at the microglia, thereby causing neuroinflammation; however, other central nervous syst...
Autores principales: | Zhao, Ya-Fei, Ren, Wen-Jing, Zhang, Ying, He, Jin-Rong, Yin, Hai-Yan, Liao, Yang, Rubini, Patrizia, Deussing, Jan M., Verkhratsky, Alexei, Yuan, Zeng-Qiang, Illes, Peter, Tang, Yong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836505/ https://www.ncbi.nlm.nih.gov/pubmed/35163829 http://dx.doi.org/10.3390/ijms23031904 |
Ejemplares similares
-
The anti-inflammatory astrocyte revealed: the role of the microbiome in shaping brain defences
por: Verkhratsky, Alexei, et al.
Publicado: (2021) -
Regulation of Microglial Functions by Purinergic Mechanisms in the Healthy and Diseased CNS
por: Illes, Peter, et al.
Publicado: (2020) -
ATP indirectly stimulates hippocampal CA1 and CA3 pyramidal neurons via the activation of neighboring P2X7 receptor-bearing astrocytes and NG2 glial cells, respectively
por: Zhang, Ying, et al.
Publicado: (2022) -
Caloric restriction triggers morphofunctional remodeling of astrocytes and enhances synaptic plasticity in the mouse hippocampus
por: Popov, Alexander, et al.
Publicado: (2020) -
GABAergic astrocytes in Alzheimer’s disease
por: Garaschuk, Olga, et al.
Publicado: (2019)