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Poly-Lysine Dendritic Nanocarrier to Target Epidermal Growth Factor Receptor Overexpressed Breast Cancer for Methotrexate Delivery

A fourth generation poly-lysine dendritic nanocarrier (P(4)LDN)-based targeted chemotherapy for breast cancer is attempted by incorporating an epidermal growth factor receptor (EGFR)-specific short peptide E2 (ARSHVGYTGAR) and the drug methotrexate (MTX) into a nanocarrier system. The drug is incorp...

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Detalles Bibliográficos
Autores principales: Narayanan, Pratibha, Anitha, Anju Krishnan, Ajayakumar, Neethu, Kumar, Kesavakurup Santhosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836561/
https://www.ncbi.nlm.nih.gov/pubmed/35160746
http://dx.doi.org/10.3390/ma15030800

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