Cargando…

Inhibition of the Monocarboxylate Transporter 1 (MCT1) Promotes 3T3-L1 Adipocyte Proliferation and Enhances Insulin Sensitivity

Enlarged, hypertrophic adipocytes are less responsive to insulin and are a hallmark feature of obesity, contributing to many of the negative metabolic consequences of excess adipose tissue. Although the mechanisms remain unclear, the adipocyte size appears to be inversely correlated with insulin sen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bailey, Tracey, Nieto, Ainhoa, McDonald, Patricia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836706/ https://www.ncbi.nlm.nih.gov/pubmed/35163825 http://dx.doi.org/10.3390/ijms23031901

Ejemplares similares

Monocarboxylate Transporter 1 (MCT1) in Liver Pathology
por: Droździk, Marek, et al.
Publicado: (2020)

Monocarboxylate Transporter 1 (MCT1) Mediates Succinate Export in the Retina
por: Bisbach, Celia M., et al.
Publicado: (2022)

Monocarboxylate Transporter 1 (MCT1) is an independent prognostic biomarker in endometrial cancer
por: Latif, Ayşe, et al.
Publicado: (2017)

Natural Autoimmunity to the Thyroid Hormone Monocarboxylate Transporters MCT8 and MCT10
por: Porst, Theresa, et al.
Publicado: (2021)

Monocarboxylate Transporters 1–4 in NSCLC: MCT1 Is an Independent Prognostic Marker for Survival
por: Eilertsen, Marte, et al.
Publicado: (2014)

Regulation of Acetate Utilization by Monocarboxylate Transporter 1 (MCT1) in Hepatocellular Carcinoma (HCC)
por: Jeon, Jeong Yong, et al.
Publicado: (2018)

The Hepatic Monocarboxylate Transporter 1 (MCT1) Contributes to the Regulation of Food Anticipation in Mice
por: Martini, Tomaz, et al.
Publicado: (2021)

Inhibition of monocarboxylate transporters (MCT) 1 and 4 reduces exercise capacity in mice
por: Kitaoka, Yu, et al.
Publicado: (2022)

Role of Human Monocarboxylate Transporter 1 (hMCT1) and 4 (hMCT4) in Tumor Cells and the Tumor Microenvironment
por: Liu, Tian, et al.
Publicado: (2023)

Butyric acid increases transepithelial transport of ferulic acid through upregulation of the monocarboxylate transporters SLC16A1 (MCT1) and SLC16A3 (MCT4)
por: Ziegler, Kerstin, et al.
Publicado: (2016)

Monocarboxylate transporter-1 (MCT1) protein expression in head and neck cancer affects clinical outcome
por: Leu, Martin, et al.
Publicado: (2021)

High expression of monocarboxylate transporter 4 (MCT 4), but not MCT 1, predicts poor prognosis in patients with non-small cell lung cancer
por: Tong, Ying-Hui, et al.
Publicado: (2021)

Monocarboxylate Transporter 4 (MCT4) Overexpression Is Correlated with Poor Prognosis of Osteosarcoma
por: Liu, Yannan, et al.
Publicado: (2019)

Role and Clinical Significance of Monocarboxylate Transporter 8 (MCT8) During Pregnancy
por: Thomas, Jinsu, et al.
Publicado: (2023)

MCT1 in Invasive Ductal Carcinoma: Monocarboxylate Metabolism and Aggressive Breast Cancer
por: Johnson, Jennifer M., et al.
Publicado: (2017)

Impact of the Monocarboxylate Transporter-1 (MCT1)-Mediated Cellular Import of Lactate on Stemness Properties of Human Pancreatic Adenocarcinoma Cells †
por: Sandforth, Leontine, et al.
Publicado: (2020)

Indole Derivatives as New Structural Class of Potent and Antiproliferative Inhibitors of Monocarboxylate Transporter 1 (MCT1; SLC16A1)
por: Puri, Sachin, et al.
Publicado: (2022)

AR-C155858 is a potent inhibitor of monocarboxylate transporters MCT1 and MCT2 that binds to an intracellular site involving transmembrane helices 7–10
por: Ovens, Matthew J., et al.
Publicado: (2010)

Overcoming Monocarboxylate Transporter 8 (MCT8)-Deficiency to Promote Human Oligodendrocyte Differentiation and Myelination
por: Lee, Jae Young, et al.
Publicado: (2017)

Characterization of monocarboxylate transporters (MCTs) expression in soft tissue sarcomas: distinct prognostic impact of MCT1 sub-cellular localization
por: Pinheiro, Céline, et al.
Publicado: (2014)

Altered mRNA and Protein Expression of Monocarboxylate Transporter MCT1 in the Cerebral Cortex and Cerebellum of Prion Protein Knockout Mice
por: Ramljak, Sanja, et al.
Publicado: (2021)

Monocarboxylate transporter 1 (MCT1), a tool to stratify acute myeloid leukemia (AML) patients and a vehicle to kill cancer cells
por: Lopes-Coelho, Filipa, et al.
Publicado: (2017)

Monocarboxylate transporter 4 (MCT4) and CD147 overexpression is associated with poor prognosis in prostate cancer
por: Pértega-Gomes, Nelma, et al.
Publicado: (2011)

The inhibition of monocarboxylate transporter 2 (MCT2) by AR-C155858 is modulated by the associated ancillary protein
por: Ovens, Matthew J., et al.
Publicado: (2010)

The Neuroplastin Adhesion Molecules Are Accessory Proteins That Chaperone the Monocarboxylate Transporter MCT2 to the Neuronal Cell Surface
por: Wilson, Marieangela C., et al.
Publicado: (2013)

Crucial Residue Involved in L-Lactate Recognition by Human Monocarboxylate Transporter 4 (hMCT4)
por: Sasaki, Shotaro, et al.
Publicado: (2013)

TMEM67, TMEM237, and Embigin in Complex With Monocarboxylate Transporter MCT1 Are Unique Components of the Photoreceptor Outer Segment Plasma Membrane
por: Skiba, Nikolai P., et al.
Publicado: (2021)

Lactate fluxes mediated by the monocarboxylate transporter-1 are key determinants of the metabolic activity of beige adipocytes
por: Lagarde, Damien, et al.
Publicado: (2020)

Mammalian monocarboxylate transporter 7 (MCT7/Slc16a6) is a novel facilitative taurine transporter
por: Higuchi, Kei, et al.
Publicado: (2022)

The genetic variation in Monocarboxylic acid transporter 2 (MCT2) has functional and clinical relevance with male infertility
por: Lee, Jinu, et al.
Publicado: (2014)

Monocarboxylate transporter 1 and monocarboxylate transporter 4 in cancer-endothelial co-culturing microenvironments promote proliferation, migration, and invasion of renal cancer cells
por: Guo, Chen, et al.
Publicado: (2019)

Monocarboxylate Transporter 13 (MCT13/SLC16A13) Functions as a Novel Plasma Membrane Oligopeptide Transporter
por: Higuchi, Kei, et al.
Publicado: (2023)

Autoregulation of H(+)/lactate efflux prevents monocarboxylate transport (MCT) inhibitors from reducing glycolytic lactic acid production
por: Blaszczak, Wiktoria, et al.
Publicado: (2022)

Monocarboxylate Transporter 4 (MCT4) Knockout Mice Have Attenuated 4NQO Induced Carcinogenesis; A Role for MCT4 in Driving Oral Squamous Cell Cancer
por: Bisetto, Sara, et al.
Publicado: (2018)

Monocarboxylate Transporters 1 and 4 and MTCO1 in Gastric Cancer
por: Eskuri, Maarit, et al.
Publicado: (2021)

Monocarboxylate transporters in cancer
por: Payen, Valéry L., et al.
Publicado: (2019)

MCT1 and MCT4 Expression and Lactate Flux Activity Increase During White and Brown Adipogenesis and Impact Adipocyte Metabolism
por: Petersen, Charlotte, et al.
Publicado: (2017)

Comprehensive Analysis of Monocarboxylate Transporter 4 (MCT4) expression in breast cancer prognosis and immune infiltration via integrated bioinformatics analysis
por: Yuan, Chen, et al.
Publicado: (2021)

A Holistic Evolutionary and 3D Pharmacophore Modelling Study Provides Insights into the Metabolism, Function, and Substrate Selectivity of the Human Monocarboxylate Transporter 4 (hMCT4)
por: Papakonstantinou, Eleni, et al.
Publicado: (2021)

Lactate/pyruvate transporter MCT-1 is a direct Wnt target that confers sensitivity to 3-bromopyruvate in colon cancer
por: Sprowl-Tanio, Stephanie, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_2qoshmmugn4fftn6s320itspiq