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Incidence of SARS-CoV-2 Infection and Related Mortality by Education Level during Three Phases of the 2020 Pandemic: A Population-Based Cohort Study in Rome

Evidence on social determinants of health on the risk of SARS-CoV-2 infection and adverse outcomes is still limited. Therefore, this work investigates educational disparities in the incidence of infection and mortality within 30 days of the onset of infection during 2020 in Rome, with particular att...

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Autores principales: Angelici, Laura, Sorge, Chiara, Di Martino, Mirko, Cappai, Giovanna, Stafoggia, Massimo, Agabiti, Nera, Girardi, Enrico, Lanini, Simone, Nicastri, Emanuele, Davoli, Marina, Cesaroni, Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836834/
https://www.ncbi.nlm.nih.gov/pubmed/35160328
http://dx.doi.org/10.3390/jcm11030877
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author Angelici, Laura
Sorge, Chiara
Di Martino, Mirko
Cappai, Giovanna
Stafoggia, Massimo
Agabiti, Nera
Girardi, Enrico
Lanini, Simone
Nicastri, Emanuele
Davoli, Marina
Cesaroni, Giulia
author_facet Angelici, Laura
Sorge, Chiara
Di Martino, Mirko
Cappai, Giovanna
Stafoggia, Massimo
Agabiti, Nera
Girardi, Enrico
Lanini, Simone
Nicastri, Emanuele
Davoli, Marina
Cesaroni, Giulia
author_sort Angelici, Laura
collection PubMed
description Evidence on social determinants of health on the risk of SARS-CoV-2 infection and adverse outcomes is still limited. Therefore, this work investigates educational disparities in the incidence of infection and mortality within 30 days of the onset of infection during 2020 in Rome, with particular attention to changes in socioeconomic inequalities over time. A cohort of 1,538,231 residents in Rome on 1 January 2020, aged 35+, followed from 1 March to 31 December 2020, were considered. Cumulative incidence and mortality rates by education were estimated. Multivariable log-binomial and Cox regression models were used to investigate educational disparities in the incidence of SARS-CoV-2 infection and mortality during the entire study period and in three phases of the pandemic. During 2020, there were 47,736 incident cases and 2281 deaths. The association between education and the incidence of infection changed over time. Till May 2020, low- and medium-educated individuals had a lower risk of infection than that of the highly educated. However, there was no evidence of an association between education and the incidence of SARS-CoV-2 infection during the summer. Lastly, low-educated adults had a 25% higher risk of infection from September to December than that of the highly educated. Similarly, there was substantial evidence of educational inequalities in mortality within 30 days of the onset of infection in the last term of 2020. In Rome, social inequalities in COVID-19 appeared in the last term of 2020, and they strengthen the need for monitoring inequalities emerging from this pandemic.
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spelling pubmed-88368342022-02-12 Incidence of SARS-CoV-2 Infection and Related Mortality by Education Level during Three Phases of the 2020 Pandemic: A Population-Based Cohort Study in Rome Angelici, Laura Sorge, Chiara Di Martino, Mirko Cappai, Giovanna Stafoggia, Massimo Agabiti, Nera Girardi, Enrico Lanini, Simone Nicastri, Emanuele Davoli, Marina Cesaroni, Giulia J Clin Med Article Evidence on social determinants of health on the risk of SARS-CoV-2 infection and adverse outcomes is still limited. Therefore, this work investigates educational disparities in the incidence of infection and mortality within 30 days of the onset of infection during 2020 in Rome, with particular attention to changes in socioeconomic inequalities over time. A cohort of 1,538,231 residents in Rome on 1 January 2020, aged 35+, followed from 1 March to 31 December 2020, were considered. Cumulative incidence and mortality rates by education were estimated. Multivariable log-binomial and Cox regression models were used to investigate educational disparities in the incidence of SARS-CoV-2 infection and mortality during the entire study period and in three phases of the pandemic. During 2020, there were 47,736 incident cases and 2281 deaths. The association between education and the incidence of infection changed over time. Till May 2020, low- and medium-educated individuals had a lower risk of infection than that of the highly educated. However, there was no evidence of an association between education and the incidence of SARS-CoV-2 infection during the summer. Lastly, low-educated adults had a 25% higher risk of infection from September to December than that of the highly educated. Similarly, there was substantial evidence of educational inequalities in mortality within 30 days of the onset of infection in the last term of 2020. In Rome, social inequalities in COVID-19 appeared in the last term of 2020, and they strengthen the need for monitoring inequalities emerging from this pandemic. MDPI 2022-02-07 /pmc/articles/PMC8836834/ /pubmed/35160328 http://dx.doi.org/10.3390/jcm11030877 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Angelici, Laura
Sorge, Chiara
Di Martino, Mirko
Cappai, Giovanna
Stafoggia, Massimo
Agabiti, Nera
Girardi, Enrico
Lanini, Simone
Nicastri, Emanuele
Davoli, Marina
Cesaroni, Giulia
Incidence of SARS-CoV-2 Infection and Related Mortality by Education Level during Three Phases of the 2020 Pandemic: A Population-Based Cohort Study in Rome
title Incidence of SARS-CoV-2 Infection and Related Mortality by Education Level during Three Phases of the 2020 Pandemic: A Population-Based Cohort Study in Rome
title_full Incidence of SARS-CoV-2 Infection and Related Mortality by Education Level during Three Phases of the 2020 Pandemic: A Population-Based Cohort Study in Rome
title_fullStr Incidence of SARS-CoV-2 Infection and Related Mortality by Education Level during Three Phases of the 2020 Pandemic: A Population-Based Cohort Study in Rome
title_full_unstemmed Incidence of SARS-CoV-2 Infection and Related Mortality by Education Level during Three Phases of the 2020 Pandemic: A Population-Based Cohort Study in Rome
title_short Incidence of SARS-CoV-2 Infection and Related Mortality by Education Level during Three Phases of the 2020 Pandemic: A Population-Based Cohort Study in Rome
title_sort incidence of sars-cov-2 infection and related mortality by education level during three phases of the 2020 pandemic: a population-based cohort study in rome
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836834/
https://www.ncbi.nlm.nih.gov/pubmed/35160328
http://dx.doi.org/10.3390/jcm11030877
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