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Upregulation of Cathepsin X in Glioblastoma: Interplay with γ-Enolase and the Effects of Selective Cathepsin X Inhibitors
Glioblastoma (GBM) is the most common and deadly primary brain tumor in adults. Understanding GBM pathobiology and discovering novel therapeutic targets are critical to finding efficient treatments. Upregulation of the lysosomal cysteine carboxypeptidase cathepsin X has been linked to immune dysfunc...
Autores principales: | Majc, Bernarda, Habič, Anamarija, Novak, Metka, Rotter, Ana, Porčnik, Andrej, Mlakar, Jernej, Župunski, Vera, Fonović, Urša Pečar, Knez, Damijan, Zidar, Nace, Gobec, Stanislav, Kos, Janko, Turnšek, Tamara Lah, Pišlar, Anja, Breznik, Barbara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836869/ https://www.ncbi.nlm.nih.gov/pubmed/35163706 http://dx.doi.org/10.3390/ijms23031784 |
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