Proglumide Reverses Nonalcoholic Steatohepatitis by Interaction with the Farnesoid X Receptor and Altering the Microbiome

Nonalcoholic steatohepatitis (NASH) is associated with obesity, metabolic syndrome, and dysbiosis of the gut microbiome. Cholecystokinin (CCK) is released by saturated fats and plays an important role in bile acid secretion. CCK receptors are expressed on cholangiocytes, and CCK-B receptor expressio...

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Autores principales: Gay, Martha D., Cao, Hong, Shivapurkar, Narayan, Dakshanamurthy, Sivanesan, Kallakury, Bhaskar, Tucker, Robin D., Kwagyan, John, Smith, Jill P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836891/
https://www.ncbi.nlm.nih.gov/pubmed/35163821
http://dx.doi.org/10.3390/ijms23031899

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