Interactions between Radiation and One-Carbon Metabolism

Metabolic reprogramming is a hallmark of cancer. Cancer cells rewire one-carbon metabolism, a central metabolic pathway, to turn nutritional inputs into essential biomolecules required for cancer cell growth and maintenance. Radiation therapy, a common cancer therapy, also interacts and alters one-c...

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Detalles Bibliográficos
Autores principales: Korimerla, Navyateja, Wahl, Daniel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836916/
https://www.ncbi.nlm.nih.gov/pubmed/35163841
http://dx.doi.org/10.3390/ijms23031919
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author Korimerla, Navyateja
Wahl, Daniel R.
author_facet Korimerla, Navyateja
Wahl, Daniel R.
author_sort Korimerla, Navyateja
collection PubMed
description Metabolic reprogramming is a hallmark of cancer. Cancer cells rewire one-carbon metabolism, a central metabolic pathway, to turn nutritional inputs into essential biomolecules required for cancer cell growth and maintenance. Radiation therapy, a common cancer therapy, also interacts and alters one-carbon metabolism. This review discusses the interactions between radiation therapy, one-carbon metabolism and its component metabolic pathways.
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spelling pubmed-88369162022-02-12 Interactions between Radiation and One-Carbon Metabolism Korimerla, Navyateja Wahl, Daniel R. Int J Mol Sci Review Metabolic reprogramming is a hallmark of cancer. Cancer cells rewire one-carbon metabolism, a central metabolic pathway, to turn nutritional inputs into essential biomolecules required for cancer cell growth and maintenance. Radiation therapy, a common cancer therapy, also interacts and alters one-carbon metabolism. This review discusses the interactions between radiation therapy, one-carbon metabolism and its component metabolic pathways. MDPI 2022-02-08 /pmc/articles/PMC8836916/ /pubmed/35163841 http://dx.doi.org/10.3390/ijms23031919 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Korimerla, Navyateja
Wahl, Daniel R.
Interactions between Radiation and One-Carbon Metabolism
title Interactions between Radiation and One-Carbon Metabolism
title_full Interactions between Radiation and One-Carbon Metabolism
title_fullStr Interactions between Radiation and One-Carbon Metabolism
title_full_unstemmed Interactions between Radiation and One-Carbon Metabolism
title_short Interactions between Radiation and One-Carbon Metabolism
title_sort interactions between radiation and one-carbon metabolism
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836916/
https://www.ncbi.nlm.nih.gov/pubmed/35163841
http://dx.doi.org/10.3390/ijms23031919
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