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Influence of Dry Eye Disease on the Measurement Repeatability of Corneal Curvature Radius and Axial Length in Patients with Cataract
The influence of dry eye disease (DED) on ocular biometric measurements is unclear. We aimed to investigate the effect of DED on the repeatability of ocular biometric measurements in cataract patients. Overall, 114 eyes scheduled for cataract surgery were enrolled. Before surgery, DED parameters inc...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837034/ https://www.ncbi.nlm.nih.gov/pubmed/35160160 http://dx.doi.org/10.3390/jcm11030710 |
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author | Hiraoka, Takahiro Asano, Hiroki Ogami, Tomohiro Nakano, Shinichiro Okamoto, Yoshifumi Yamada, Yoshiaki Oshika, Tetsuro |
author_facet | Hiraoka, Takahiro Asano, Hiroki Ogami, Tomohiro Nakano, Shinichiro Okamoto, Yoshifumi Yamada, Yoshiaki Oshika, Tetsuro |
author_sort | Hiraoka, Takahiro |
collection | PubMed |
description | The influence of dry eye disease (DED) on ocular biometric measurements is unclear. We aimed to investigate the effect of DED on the repeatability of ocular biometric measurements in cataract patients. Overall, 114 eyes scheduled for cataract surgery were enrolled. Before surgery, DED parameters including tear film break-up time (BUT), corneal and conjunctival staining scores, and subjective symptoms were examined. Corneal curvature radius and axial length were assessed twice on the same day using IOLMaster-500 (Carl Zeiss Meditec), and the absolute difference between the two measurements was calculated and used as an index of measurement repeatability. The measurement repeatability of the steep meridian of corneal curvature radius was significantly worse in eyes with DED than in those without DED (p = 0.044) and was significantly associated with BUT (r = −0.206, p = 0.031). The measurement repeatability of axial length was negatively correlated with BUT (r = −0.199, p = 0.041) and positively correlated with the corneal staining score (r = 0.253, p = 0.009). In conclusion, the measurement repeatability of corneal curvature radius declined in eyes with DED. Shortened BUTs were associated with a deterioration in the measurement repeatability of corneal curvature radius and axial length. |
format | Online Article Text |
id | pubmed-8837034 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-88370342022-02-12 Influence of Dry Eye Disease on the Measurement Repeatability of Corneal Curvature Radius and Axial Length in Patients with Cataract Hiraoka, Takahiro Asano, Hiroki Ogami, Tomohiro Nakano, Shinichiro Okamoto, Yoshifumi Yamada, Yoshiaki Oshika, Tetsuro J Clin Med Article The influence of dry eye disease (DED) on ocular biometric measurements is unclear. We aimed to investigate the effect of DED on the repeatability of ocular biometric measurements in cataract patients. Overall, 114 eyes scheduled for cataract surgery were enrolled. Before surgery, DED parameters including tear film break-up time (BUT), corneal and conjunctival staining scores, and subjective symptoms were examined. Corneal curvature radius and axial length were assessed twice on the same day using IOLMaster-500 (Carl Zeiss Meditec), and the absolute difference between the two measurements was calculated and used as an index of measurement repeatability. The measurement repeatability of the steep meridian of corneal curvature radius was significantly worse in eyes with DED than in those without DED (p = 0.044) and was significantly associated with BUT (r = −0.206, p = 0.031). The measurement repeatability of axial length was negatively correlated with BUT (r = −0.199, p = 0.041) and positively correlated with the corneal staining score (r = 0.253, p = 0.009). In conclusion, the measurement repeatability of corneal curvature radius declined in eyes with DED. Shortened BUTs were associated with a deterioration in the measurement repeatability of corneal curvature radius and axial length. MDPI 2022-01-28 /pmc/articles/PMC8837034/ /pubmed/35160160 http://dx.doi.org/10.3390/jcm11030710 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Hiraoka, Takahiro Asano, Hiroki Ogami, Tomohiro Nakano, Shinichiro Okamoto, Yoshifumi Yamada, Yoshiaki Oshika, Tetsuro Influence of Dry Eye Disease on the Measurement Repeatability of Corneal Curvature Radius and Axial Length in Patients with Cataract |
title | Influence of Dry Eye Disease on the Measurement Repeatability of Corneal Curvature Radius and Axial Length in Patients with Cataract |
title_full | Influence of Dry Eye Disease on the Measurement Repeatability of Corneal Curvature Radius and Axial Length in Patients with Cataract |
title_fullStr | Influence of Dry Eye Disease on the Measurement Repeatability of Corneal Curvature Radius and Axial Length in Patients with Cataract |
title_full_unstemmed | Influence of Dry Eye Disease on the Measurement Repeatability of Corneal Curvature Radius and Axial Length in Patients with Cataract |
title_short | Influence of Dry Eye Disease on the Measurement Repeatability of Corneal Curvature Radius and Axial Length in Patients with Cataract |
title_sort | influence of dry eye disease on the measurement repeatability of corneal curvature radius and axial length in patients with cataract |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837034/ https://www.ncbi.nlm.nih.gov/pubmed/35160160 http://dx.doi.org/10.3390/jcm11030710 |
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