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Influence of Dry Eye Disease on the Measurement Repeatability of Corneal Curvature Radius and Axial Length in Patients with Cataract

The influence of dry eye disease (DED) on ocular biometric measurements is unclear. We aimed to investigate the effect of DED on the repeatability of ocular biometric measurements in cataract patients. Overall, 114 eyes scheduled for cataract surgery were enrolled. Before surgery, DED parameters inc...

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Autores principales: Hiraoka, Takahiro, Asano, Hiroki, Ogami, Tomohiro, Nakano, Shinichiro, Okamoto, Yoshifumi, Yamada, Yoshiaki, Oshika, Tetsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837034/
https://www.ncbi.nlm.nih.gov/pubmed/35160160
http://dx.doi.org/10.3390/jcm11030710
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author Hiraoka, Takahiro
Asano, Hiroki
Ogami, Tomohiro
Nakano, Shinichiro
Okamoto, Yoshifumi
Yamada, Yoshiaki
Oshika, Tetsuro
author_facet Hiraoka, Takahiro
Asano, Hiroki
Ogami, Tomohiro
Nakano, Shinichiro
Okamoto, Yoshifumi
Yamada, Yoshiaki
Oshika, Tetsuro
author_sort Hiraoka, Takahiro
collection PubMed
description The influence of dry eye disease (DED) on ocular biometric measurements is unclear. We aimed to investigate the effect of DED on the repeatability of ocular biometric measurements in cataract patients. Overall, 114 eyes scheduled for cataract surgery were enrolled. Before surgery, DED parameters including tear film break-up time (BUT), corneal and conjunctival staining scores, and subjective symptoms were examined. Corneal curvature radius and axial length were assessed twice on the same day using IOLMaster-500 (Carl Zeiss Meditec), and the absolute difference between the two measurements was calculated and used as an index of measurement repeatability. The measurement repeatability of the steep meridian of corneal curvature radius was significantly worse in eyes with DED than in those without DED (p = 0.044) and was significantly associated with BUT (r = −0.206, p = 0.031). The measurement repeatability of axial length was negatively correlated with BUT (r = −0.199, p = 0.041) and positively correlated with the corneal staining score (r = 0.253, p = 0.009). In conclusion, the measurement repeatability of corneal curvature radius declined in eyes with DED. Shortened BUTs were associated with a deterioration in the measurement repeatability of corneal curvature radius and axial length.
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spelling pubmed-88370342022-02-12 Influence of Dry Eye Disease on the Measurement Repeatability of Corneal Curvature Radius and Axial Length in Patients with Cataract Hiraoka, Takahiro Asano, Hiroki Ogami, Tomohiro Nakano, Shinichiro Okamoto, Yoshifumi Yamada, Yoshiaki Oshika, Tetsuro J Clin Med Article The influence of dry eye disease (DED) on ocular biometric measurements is unclear. We aimed to investigate the effect of DED on the repeatability of ocular biometric measurements in cataract patients. Overall, 114 eyes scheduled for cataract surgery were enrolled. Before surgery, DED parameters including tear film break-up time (BUT), corneal and conjunctival staining scores, and subjective symptoms were examined. Corneal curvature radius and axial length were assessed twice on the same day using IOLMaster-500 (Carl Zeiss Meditec), and the absolute difference between the two measurements was calculated and used as an index of measurement repeatability. The measurement repeatability of the steep meridian of corneal curvature radius was significantly worse in eyes with DED than in those without DED (p = 0.044) and was significantly associated with BUT (r = −0.206, p = 0.031). The measurement repeatability of axial length was negatively correlated with BUT (r = −0.199, p = 0.041) and positively correlated with the corneal staining score (r = 0.253, p = 0.009). In conclusion, the measurement repeatability of corneal curvature radius declined in eyes with DED. Shortened BUTs were associated with a deterioration in the measurement repeatability of corneal curvature radius and axial length. MDPI 2022-01-28 /pmc/articles/PMC8837034/ /pubmed/35160160 http://dx.doi.org/10.3390/jcm11030710 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Hiraoka, Takahiro
Asano, Hiroki
Ogami, Tomohiro
Nakano, Shinichiro
Okamoto, Yoshifumi
Yamada, Yoshiaki
Oshika, Tetsuro
Influence of Dry Eye Disease on the Measurement Repeatability of Corneal Curvature Radius and Axial Length in Patients with Cataract
title Influence of Dry Eye Disease on the Measurement Repeatability of Corneal Curvature Radius and Axial Length in Patients with Cataract
title_full Influence of Dry Eye Disease on the Measurement Repeatability of Corneal Curvature Radius and Axial Length in Patients with Cataract
title_fullStr Influence of Dry Eye Disease on the Measurement Repeatability of Corneal Curvature Radius and Axial Length in Patients with Cataract
title_full_unstemmed Influence of Dry Eye Disease on the Measurement Repeatability of Corneal Curvature Radius and Axial Length in Patients with Cataract
title_short Influence of Dry Eye Disease on the Measurement Repeatability of Corneal Curvature Radius and Axial Length in Patients with Cataract
title_sort influence of dry eye disease on the measurement repeatability of corneal curvature radius and axial length in patients with cataract
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837034/
https://www.ncbi.nlm.nih.gov/pubmed/35160160
http://dx.doi.org/10.3390/jcm11030710
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