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T-Cell-Specific CerS4 Depletion Prolonged Inflammation and Enhanced Tumor Burden in the AOM/DSS-Induced CAC Model

To better understand the role of sphingolipids in the multifactorial process of inflammatory bowel disease (IBD), we elucidated the role of CerS4 in colitis and colitis-associated cancer (CAC). For this, we utilized the azoxymethane/dextran sodium sulphate (AOM/DSS)-induced colitis model in global C...

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Detalles Bibliográficos
Autores principales:	El-Hindi, Khadija, Brachtendorf, Sebastian, Hartel, Jennifer Christina, Oertel, Stephanie, Birod, Kerstin, Merz, Nadine, Trautmann, Sandra, Thomas, Dominique, Weigert, Andreas, Schäufele, Tim J., Scholich, Klaus, Schiffmann, Susanne, Ulshöfer, Thomas, Utermöhlen, Olaf, Grösch, Sabine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837088/ https://www.ncbi.nlm.nih.gov/pubmed/35163788 http://dx.doi.org/10.3390/ijms23031866

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