Antibody–drug conjugates harboring a kinesin spindle protein inhibitor with immunostimulatory properties

Antibody–drug conjugates (ADCs) are used to target cancer cells by means of antibodies directed to tumor-associated antigens, causing the incorporation of a cytotoxic payload into target cells. Here, we characterized the mode of action of ADC costing of a TWEAKR-specific monoclonal antibody conjugat...

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Detalles Bibliográficos
Autores principales: Sommer, Anette, Berndt, Sandra, Lerchen, Hans-Georg, Forveille, Sabrina, Sauvat, Allan, Mumberg, Dominik, Kroemer, Guido, Kepp, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837233/
https://www.ncbi.nlm.nih.gov/pubmed/35154909
http://dx.doi.org/10.1080/2162402X.2022.2037216

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