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Glaucoma and optical coherence tomography changes in migraine: A comparative cross-sectional study
PURPOSE: To study the prevalence of glaucoma among adults with migraine and the effect of migraine on peripapillary retinal nerve fiber layer (pRNFL) and central macular thickness (CMT) using optical coherence tomography (OCT) compared to those without migraine headache, i.e. in tension-type headach...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837329/ https://www.ncbi.nlm.nih.gov/pubmed/34826993 http://dx.doi.org/10.4103/ijo.IJO_375_21 |
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author | Panicker, Gayathri Kaliaperumal, Subashini Narayan, Sunil Mani, Malavika |
author_facet | Panicker, Gayathri Kaliaperumal, Subashini Narayan, Sunil Mani, Malavika |
author_sort | Panicker, Gayathri |
collection | PubMed |
description | PURPOSE: To study the prevalence of glaucoma among adults with migraine and the effect of migraine on peripapillary retinal nerve fiber layer (pRNFL) and central macular thickness (CMT) using optical coherence tomography (OCT) compared to those without migraine headache, i.e. in tension-type headache (TTH) and normal group. METHODS: One hundred and eleven patients (222 eyes) were recruited in three groups. migraine, TTH, and normal subjects visiting hospital outpatient services. After noting demographic details and pertinent history, ophthalmological evaluation including optic disc for glaucomatous changes along with computerized visual field testing and OCT for pRNFL thickness and CMT was performed in all eyes. Continuous variables were compared using ANOVA or Kruskal–Wallis test, while categorical variables including the association of glaucoma with migraine were analyzed using Chi-square or Fisher’s exact test. RESULTS: Prevalence of glaucoma in migraine group (12.2%) was more than in comparison groups (6.8% in TTH, 4.1% in normal) which was however not significant (Fisher’s exact P = 0.207). Average pRNFL thickness (103.59 ± 12.82 μm) and thickness in nasal (90.49 ± 19.19 μm) and temporal quadrants (70.58 ± 16.13 μm) and CMT (213.78 ± 19.81 μm) were significantly reduced (ANOVA P < 0.05) in migraine patients when compared to the other groups and this was independent of the presence of glaucoma. CONCLUSION: Prevalence of glaucoma is not significantly higher in migraine patients. However, migraine causes thinning of retinal layers on OCT that is statistically significant. |
format | Online Article Text |
id | pubmed-8837329 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-88373292022-03-07 Glaucoma and optical coherence tomography changes in migraine: A comparative cross-sectional study Panicker, Gayathri Kaliaperumal, Subashini Narayan, Sunil Mani, Malavika Indian J Ophthalmol Special Focus, Glaucoma, Original Article PURPOSE: To study the prevalence of glaucoma among adults with migraine and the effect of migraine on peripapillary retinal nerve fiber layer (pRNFL) and central macular thickness (CMT) using optical coherence tomography (OCT) compared to those without migraine headache, i.e. in tension-type headache (TTH) and normal group. METHODS: One hundred and eleven patients (222 eyes) were recruited in three groups. migraine, TTH, and normal subjects visiting hospital outpatient services. After noting demographic details and pertinent history, ophthalmological evaluation including optic disc for glaucomatous changes along with computerized visual field testing and OCT for pRNFL thickness and CMT was performed in all eyes. Continuous variables were compared using ANOVA or Kruskal–Wallis test, while categorical variables including the association of glaucoma with migraine were analyzed using Chi-square or Fisher’s exact test. RESULTS: Prevalence of glaucoma in migraine group (12.2%) was more than in comparison groups (6.8% in TTH, 4.1% in normal) which was however not significant (Fisher’s exact P = 0.207). Average pRNFL thickness (103.59 ± 12.82 μm) and thickness in nasal (90.49 ± 19.19 μm) and temporal quadrants (70.58 ± 16.13 μm) and CMT (213.78 ± 19.81 μm) were significantly reduced (ANOVA P < 0.05) in migraine patients when compared to the other groups and this was independent of the presence of glaucoma. CONCLUSION: Prevalence of glaucoma is not significantly higher in migraine patients. However, migraine causes thinning of retinal layers on OCT that is statistically significant. Wolters Kluwer - Medknow 2021-12 2021-11-26 /pmc/articles/PMC8837329/ /pubmed/34826993 http://dx.doi.org/10.4103/ijo.IJO_375_21 Text en Copyright: © 2021 Indian Journal of Ophthalmology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 4.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Special Focus, Glaucoma, Original Article Panicker, Gayathri Kaliaperumal, Subashini Narayan, Sunil Mani, Malavika Glaucoma and optical coherence tomography changes in migraine: A comparative cross-sectional study |
title | Glaucoma and optical coherence tomography changes in migraine: A comparative cross-sectional study |
title_full | Glaucoma and optical coherence tomography changes in migraine: A comparative cross-sectional study |
title_fullStr | Glaucoma and optical coherence tomography changes in migraine: A comparative cross-sectional study |
title_full_unstemmed | Glaucoma and optical coherence tomography changes in migraine: A comparative cross-sectional study |
title_short | Glaucoma and optical coherence tomography changes in migraine: A comparative cross-sectional study |
title_sort | glaucoma and optical coherence tomography changes in migraine: a comparative cross-sectional study |
topic | Special Focus, Glaucoma, Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837329/ https://www.ncbi.nlm.nih.gov/pubmed/34826993 http://dx.doi.org/10.4103/ijo.IJO_375_21 |
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