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Does size of telangiectasia on optical coherence tomography angiography influence vision in eyes with type 2 macular telangiectasia?
PURPOSE: To study the influence of dimensions of macular telangiectasia (MacTel) on enface optical coherence tomography angiography (OCTA) on vision and clinical parameters in eyes with MacTel type 2. METHODS: MacTel was classified based on OCTA location, i.e. either temporal to the fovea (grade 1),...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837333/ https://www.ncbi.nlm.nih.gov/pubmed/34826997 http://dx.doi.org/10.4103/ijo.IJO_315_21 |
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author | Kelkar, Aditya S Kelkar, Jai A Tidke, Sayali Agarwal, Aanchal Bolisetty, Mounika Kelkar, Shreekant |
author_facet | Kelkar, Aditya S Kelkar, Jai A Tidke, Sayali Agarwal, Aanchal Bolisetty, Mounika Kelkar, Shreekant |
author_sort | Kelkar, Aditya S |
collection | PubMed |
description | PURPOSE: To study the influence of dimensions of macular telangiectasia (MacTel) on enface optical coherence tomography angiography (OCTA) on vision and clinical parameters in eyes with MacTel type 2. METHODS: MacTel was classified based on OCTA location, i.e. either temporal to the fovea (grade 1), or spread nasally (grade 2), or circumferentially (grade 3), or the presence of neovascular-like tissue in the outer retina–choriocapillary complex (ORCC) (grade 4). On enface images, the maximum dimensions of the MacTel in the deep plexus were noted using calipers by a single experienced observer. RESULTS: Ninety-eight eyes of 49 patients with MacTel with a mean visual acuity was 0.46 + 0.26 logMAR and mean macular thickness of 202 ± 132 μ were included. Based on OCTA, grade 3 MacTel (n = 35, 36%) was the commonest followed by grade 4 (n = 28, 29%). The mean maximum vertical diameter of the MacTel was 2019 + 753 μ, and every 500 microns increment in vertical diameter of the MacTel was associated with a half-line drop in vision (95%CI = 0.005 to 0.08 logMAR, P = 0.03). Vision gradually reduced with increment in OCTA grades of MacTel from grade 1 to 3; however, the trend was not maintained in grade 4 MacTel, which showed better vision and lesser degenerative cysts. CONCLUSION: Larger telangiectasias were associated with significantly lower vision in MacTel. Eyes with deeper telangiectasia involving ORCC have better vision and evidence of far lesser neurodegeneration than type 3 disease, suggesting that this may not be part of the continuum and does not represent neovascularization. |
format | Online Article Text |
id | pubmed-8837333 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-88373332022-03-07 Does size of telangiectasia on optical coherence tomography angiography influence vision in eyes with type 2 macular telangiectasia? Kelkar, Aditya S Kelkar, Jai A Tidke, Sayali Agarwal, Aanchal Bolisetty, Mounika Kelkar, Shreekant Indian J Ophthalmol Special Focus, Retina, Original Article PURPOSE: To study the influence of dimensions of macular telangiectasia (MacTel) on enface optical coherence tomography angiography (OCTA) on vision and clinical parameters in eyes with MacTel type 2. METHODS: MacTel was classified based on OCTA location, i.e. either temporal to the fovea (grade 1), or spread nasally (grade 2), or circumferentially (grade 3), or the presence of neovascular-like tissue in the outer retina–choriocapillary complex (ORCC) (grade 4). On enface images, the maximum dimensions of the MacTel in the deep plexus were noted using calipers by a single experienced observer. RESULTS: Ninety-eight eyes of 49 patients with MacTel with a mean visual acuity was 0.46 + 0.26 logMAR and mean macular thickness of 202 ± 132 μ were included. Based on OCTA, grade 3 MacTel (n = 35, 36%) was the commonest followed by grade 4 (n = 28, 29%). The mean maximum vertical diameter of the MacTel was 2019 + 753 μ, and every 500 microns increment in vertical diameter of the MacTel was associated with a half-line drop in vision (95%CI = 0.005 to 0.08 logMAR, P = 0.03). Vision gradually reduced with increment in OCTA grades of MacTel from grade 1 to 3; however, the trend was not maintained in grade 4 MacTel, which showed better vision and lesser degenerative cysts. CONCLUSION: Larger telangiectasias were associated with significantly lower vision in MacTel. Eyes with deeper telangiectasia involving ORCC have better vision and evidence of far lesser neurodegeneration than type 3 disease, suggesting that this may not be part of the continuum and does not represent neovascularization. Wolters Kluwer - Medknow 2021-12 2021-11-26 /pmc/articles/PMC8837333/ /pubmed/34826997 http://dx.doi.org/10.4103/ijo.IJO_315_21 Text en Copyright: © 2021 Indian Journal of Ophthalmology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 4.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Special Focus, Retina, Original Article Kelkar, Aditya S Kelkar, Jai A Tidke, Sayali Agarwal, Aanchal Bolisetty, Mounika Kelkar, Shreekant Does size of telangiectasia on optical coherence tomography angiography influence vision in eyes with type 2 macular telangiectasia? |
title | Does size of telangiectasia on optical coherence tomography angiography influence vision in eyes with type 2 macular telangiectasia? |
title_full | Does size of telangiectasia on optical coherence tomography angiography influence vision in eyes with type 2 macular telangiectasia? |
title_fullStr | Does size of telangiectasia on optical coherence tomography angiography influence vision in eyes with type 2 macular telangiectasia? |
title_full_unstemmed | Does size of telangiectasia on optical coherence tomography angiography influence vision in eyes with type 2 macular telangiectasia? |
title_short | Does size of telangiectasia on optical coherence tomography angiography influence vision in eyes with type 2 macular telangiectasia? |
title_sort | does size of telangiectasia on optical coherence tomography angiography influence vision in eyes with type 2 macular telangiectasia? |
topic | Special Focus, Retina, Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837333/ https://www.ncbi.nlm.nih.gov/pubmed/34826997 http://dx.doi.org/10.4103/ijo.IJO_315_21 |
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