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PFKFB3 Regulates Chemoresistance, Metastasis and Stemness via IAP Proteins and the NF-κB Signaling Pathway in Ovarian Cancer

Glycolysis has been reported to be critical for cancer stem cells (CSCs), which are associated with tumor chemoresistance, metastasis and recurrence. Thus, selectively targeting glycolytic enzymes may be a potential therapy for ovarian cancer. 6‐phosphofructo‐2‐kinase/fructose‐2,6‐biphosphatase 3 (P...

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Detalles Bibliográficos
Autores principales:	Jiang, Yu-xin, Siu, Michelle K. Y., Wang, Jing-jing, Leung, Thomas H. Y., Chan, David W., Cheung, Annie N. Y., Ngan, Hextan Y. S., Chan, Karen K. L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837381/ https://www.ncbi.nlm.nih.gov/pubmed/35155224 http://dx.doi.org/10.3389/fonc.2022.748403

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