The POU2F1-ALDOA axis promotes the proliferation and chemoresistance of colon cancer cells by enhancing glycolysis and the pentose phosphate pathway activity

Cancer metabolic reprogramming enhances its malignant behaviors and drug resistance, which is regulated by POU domain transcription factors. This study explored the effect of POU domain class 2 transcription factor 1 (POU2F1) on metabolic reprogramming in colon cancer. The POU2F1 expression was anal...

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Detalles Bibliográficos
Autores principales: Lin, Jinguan, Xia, Longzheng, Oyang, Linda, Liang, Jiaxin, Tan, Shiming, Wu, Nayiyuan, Yi, Pin, Pan, Qing, Rao, Shan, Han, Yaqian, Tang, Yanyan, Su, Min, Luo, Xia, Yang, Yiqing, Chen, Xiaohui, Yang, Lixia, Zhou, Yujuan, Liao, Qianjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837540/
https://www.ncbi.nlm.nih.gov/pubmed/34997215
http://dx.doi.org/10.1038/s41388-021-02148-y

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