Novel function of THEMIS2 in the enhancement of cancer stemness and chemoresistance by releasing PTP1B from MET

Triple negative breast cancer (TNBC) possesses poor prognosis mainly due to lack of effective endocrine or targeted therapies, aggressive nature and high rate of chemoresistance. Cancer stem cells (CSCs) are considered to play critical roles in cancer recurrence and chemoresistance. THEMIS2 was iden...

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Detalles Bibliográficos
Autores principales: Huang, Wei-Chieh, Yen, Jia-Hau, Sung, Yu-Wen, Tung, Shiao-Lin, Chen, Po-Ming, Chu, Pei-Yi, Shih, Ya-Chi, Chi, Hsiang-Cheng, Huang, Yi-Ching, Huang, Shih-Jei, Wang, Lu‐Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837547/
https://www.ncbi.nlm.nih.gov/pubmed/34974522
http://dx.doi.org/10.1038/s41388-021-02136-2

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