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Nudging the N170 forward with prior stimulation—Bridging the gap between N170 and recognition potential

Evoked response potentials are often divided up into numerous components, each with their own body of literature. But is there less variety than we might suppose? In this study, we nudge one component into looking like another. Both the N170 and recognition potential (RP) are N1 components in respon...

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Autores principales: Luo, Canhuang, Chen, Wei, VanRullen, Rufin, Zhang, Ye, Gaspar, Carl Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837586/
https://www.ncbi.nlm.nih.gov/pubmed/34786780
http://dx.doi.org/10.1002/hbm.25716
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author Luo, Canhuang
Chen, Wei
VanRullen, Rufin
Zhang, Ye
Gaspar, Carl Michael
author_facet Luo, Canhuang
Chen, Wei
VanRullen, Rufin
Zhang, Ye
Gaspar, Carl Michael
author_sort Luo, Canhuang
collection PubMed
description Evoked response potentials are often divided up into numerous components, each with their own body of literature. But is there less variety than we might suppose? In this study, we nudge one component into looking like another. Both the N170 and recognition potential (RP) are N1 components in response to familiar objects. However, the RP is often measured with a forward mask that ends at stimulus onset whereas the N170 is often measured with no masking at all. This study investigates how inter‐stimulus interval (ISI) may delay and distort the N170 into an RP by manipulating the temporal gap (ISI) between forward mask and target. The results revealed reverse relationships between the ISI on the one hand, and the N170 latency, single‐trial N1 jitter (an approximation of N1 width) and reaction time on the other hand. Importantly, we find that scalp topographies have a unique signature at the N1 peak across all conditions, from the longest gap (N170) to the shortest (RP). These findings prove that the mask‐delayed N1 is still the same N170, even under conditions that are normally associated with a different component like the RP. In general, our results suggest greater synthesis in the study of event related potential components.
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spelling pubmed-88375862022-02-14 Nudging the N170 forward with prior stimulation—Bridging the gap between N170 and recognition potential Luo, Canhuang Chen, Wei VanRullen, Rufin Zhang, Ye Gaspar, Carl Michael Hum Brain Mapp Research Articles Evoked response potentials are often divided up into numerous components, each with their own body of literature. But is there less variety than we might suppose? In this study, we nudge one component into looking like another. Both the N170 and recognition potential (RP) are N1 components in response to familiar objects. However, the RP is often measured with a forward mask that ends at stimulus onset whereas the N170 is often measured with no masking at all. This study investigates how inter‐stimulus interval (ISI) may delay and distort the N170 into an RP by manipulating the temporal gap (ISI) between forward mask and target. The results revealed reverse relationships between the ISI on the one hand, and the N170 latency, single‐trial N1 jitter (an approximation of N1 width) and reaction time on the other hand. Importantly, we find that scalp topographies have a unique signature at the N1 peak across all conditions, from the longest gap (N170) to the shortest (RP). These findings prove that the mask‐delayed N1 is still the same N170, even under conditions that are normally associated with a different component like the RP. In general, our results suggest greater synthesis in the study of event related potential components. John Wiley & Sons, Inc. 2021-11-17 /pmc/articles/PMC8837586/ /pubmed/34786780 http://dx.doi.org/10.1002/hbm.25716 Text en © 2021 The Authors. Human Brain Mapping published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Research Articles
Luo, Canhuang
Chen, Wei
VanRullen, Rufin
Zhang, Ye
Gaspar, Carl Michael
Nudging the N170 forward with prior stimulation—Bridging the gap between N170 and recognition potential
title Nudging the N170 forward with prior stimulation—Bridging the gap between N170 and recognition potential
title_full Nudging the N170 forward with prior stimulation—Bridging the gap between N170 and recognition potential
title_fullStr Nudging the N170 forward with prior stimulation—Bridging the gap between N170 and recognition potential
title_full_unstemmed Nudging the N170 forward with prior stimulation—Bridging the gap between N170 and recognition potential
title_short Nudging the N170 forward with prior stimulation—Bridging the gap between N170 and recognition potential
title_sort nudging the n170 forward with prior stimulation—bridging the gap between n170 and recognition potential
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837586/
https://www.ncbi.nlm.nih.gov/pubmed/34786780
http://dx.doi.org/10.1002/hbm.25716
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