Development of a skin- and neuro-attenuated live vaccine for varicella

Varicella caused by the primary infection of varicella-zoster virus (VZV) exerts a considerable disease burden globally. Current varicella vaccines consisting of the live-attenuated vOka strain of VZV are generally safe and effective. However, vOka retains full neurovirulence and can establish laten...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Pan, Dequan, Fu, Wenkun, Ye, Xiangzhong, Han, Jinle, Yang, Lianwei, Jia, Jizong, Liu, Jian, Zhu, Rui, Zhang, Yali, Liu, Che, Ye, Jianghui, Selariu, Anca, Que, Yuqiong, Zhao, Qinjian, Wu, Ting, Li, Yimin, Zhang, Jun, Cheng, Tong, Zhu, Hua, Xia, Ningshao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837607/
https://www.ncbi.nlm.nih.gov/pubmed/35149692
http://dx.doi.org/10.1038/s41467-022-28329-1

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