Autolysosomes and caspase-3 control the biogenesis and release of immunogenic apoptotic exosomes

Apoptotic exosome-like vesicles (ApoExos) are a novel type of extracellular vesicle that contribute to the propagation of inflammation at sites of vascular injury when released by dying cells. ApoExos are characterized by the presence of the C-terminal perlecan LG3 fragment and 20S proteasome, and t...

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Detalles Bibliográficos
Autores principales: Beillevaire, Déborah, Migneault, Francis, Turgeon, Julie, Gingras, Diane, Rimbaud, Annie Karakeussian, Marcoux, Geneviève, Spino, Crysta, Thibodeau, Nicolas, Bonneil, Eric, Thibault, Pierre, Boilard, Éric, Dieudé, Mélanie, Hébert, Marie-Josée
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837616/
https://www.ncbi.nlm.nih.gov/pubmed/35149669
http://dx.doi.org/10.1038/s41419-022-04591-5

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