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Telomerase is required for glomerular renewal in kidneys of adult mice

Homeostatic renal filtration relies on the integrity of podocytes, which function in glomerular filtration. These highly specialized cells are damaged in 90% of chronic kidney disease, representing the leading cause of end-stage renal failure. Although modest podocyte renewal has been documented in...

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Detalles Bibliográficos
Autores principales: Montandon, Margo, Hamidouche, Tynhinane, Yart, Lucile, Duret, Lou C., Pons, Catherine, Soubeiran, Nicolas, Pousse, Mélanie, Cervera, Ludovic, Vial, Valérie, Fassy, Julien, Croce, Olivier, Gilson, Eric, Shkreli, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837629/
https://www.ncbi.nlm.nih.gov/pubmed/35149726
http://dx.doi.org/10.1038/s41536-022-00212-z