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Mechanism of activation and the rewired network: New drug design concepts

Precision oncology benefits from effective early phase drug discovery decisions. Recently, drugging inactive protein conformations has shown impressive successes, raising the cardinal questions of which targets can profit and what are the principles of the active/inactive protein pharmacology. Cance...

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Detalles Bibliográficos
Autores principales: Nussinov, Ruth, Zhang, Mingzhen, Maloney, Ryan, Tsai, Chung‐Jung, Yavuz, Bengi Ruken, Tuncbag, Nurcan, Jang, Hyunbum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837674/
https://www.ncbi.nlm.nih.gov/pubmed/34693559
http://dx.doi.org/10.1002/med.21863