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Mechanism of activation and the rewired network: New drug design concepts
Precision oncology benefits from effective early phase drug discovery decisions. Recently, drugging inactive protein conformations has shown impressive successes, raising the cardinal questions of which targets can profit and what are the principles of the active/inactive protein pharmacology. Cance...
Autores principales: | Nussinov, Ruth, Zhang, Mingzhen, Maloney, Ryan, Tsai, Chung‐Jung, Yavuz, Bengi Ruken, Tuncbag, Nurcan, Jang, Hyunbum |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837674/ https://www.ncbi.nlm.nih.gov/pubmed/34693559 http://dx.doi.org/10.1002/med.21863 |
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