Angiogenic Gene Networks are Dysregulated in Opioid Use Disorder: Evidence from Multi-Omics and Imaging of Postmortem Human Brain

Opioid use disorder (OUD) is a public health crisis in the U.S. that causes over 50 thousand deaths annually due to overdose. Using next-generation RNA sequencing and proteomics techniques, we identified 394 differentially expressed (DE) coding and long noncoding (lnc) RNAs as well as 213 DE protein...

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Detalles Bibliográficos
Autores principales: Mendez, Emily F., Wei, Haichao, Hu, Ruifeng, Stertz, Laura, Fries, Gabriel R., Wu, Xizi, Najera, Katherine E., Monterey, Michael D., Lincoln, Christie M., Kim, Joo-won, Moriel, Karla, Meyer, Thomas D., Selvaraj, Sudhakar, Teixeira, Antonio L., Zhao, Zhongming, Xu, Junqian, Wu, Jiaqian, Walss-Bass, Consuelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837724/
https://www.ncbi.nlm.nih.gov/pubmed/34385598
http://dx.doi.org/10.1038/s41380-021-01259-y

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