miR-520a-5p regulates Frizzled 9 expression and mediates effects of cigarette smoke and iloprost chemoprevention

Expression of Frizzled 9 (FZD9) is critical to the activity of the lung cancer chemoprevention agent and prostacyclin analogue, iloprost. FZD9 is required in lung epithelial cells for iloprost to activate peroxisome proliferator activated receptor gamma (PPARG) and related anti-tumor signaling. We a...

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Detalles Bibliográficos
Autores principales: Smith, A. J., Do, P., Sompel, K., Elango, A., Tennis, M. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837775/
https://www.ncbi.nlm.nih.gov/pubmed/35149732
http://dx.doi.org/10.1038/s41598-022-06292-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837775/
https://www.ncbi.nlm.nih.gov/pubmed/35149732
http://dx.doi.org/10.1038/s41598-022-06292-7

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