Adaptive laboratory evolution in S. cerevisiae highlights role of transcription factors in fungal xenobiotic resistance

In vitro evolution and whole genome analysis were used to comprehensively identify the genetic determinants of chemical resistance in Saccharomyces cerevisiae. Sequence analysis identified many genes contributing to the resistance phenotype as well as numerous amino acids in potential targets that m...

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Detalles Bibliográficos
Autores principales: Ottilie, Sabine, Luth, Madeline R., Hellemann, Erich, Goldgof, Gregory M., Vigil, Eddy, Kumar, Prianka, Cheung, Andrea L., Song, Miranda, Godinez-Macias, Karla P., Carolino, Krypton, Yang, Jennifer, Lopez, Gisel, Abraham, Matthew, Tarsio, Maureen, LeBlanc, Emmanuelle, Whitesell, Luke, Schenken, Jake, Gunawan, Felicia, Patel, Reysha, Smith, Joshua, Love, Melissa S., Williams, Roy M., McNamara, Case W., Gerwick, William H., Ideker, Trey, Suzuki, Yo, Wirth, Dyann F., Lukens, Amanda K., Kane, Patricia M., Cowen, Leah E., Durrant, Jacob D., Winzeler, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837787/
https://www.ncbi.nlm.nih.gov/pubmed/35149760
http://dx.doi.org/10.1038/s42003-022-03076-7

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