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A Novel PIFA/KOH Promoted Approach to Synthesize C2-arylacylated Benzothiazoles as Potential Drug Scaffolds

To discover an efficient and convenient method to synthesize C2-arylacylated benzothiazoles as potential drug scaffolds, a novel [bis(trifluoroacetoxy)iodo]benzene(PIFA)/KOH synergistically promoted direct ring-opening C2-arylacylation reaction of 2H-benzothiazoles with aryl methyl ketones has been...

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Detalles Bibliográficos
Autores principales: Sun, Xiao-Tong, Hu, Zhi-Gang, Huang, Zhen, Zhou, Ling-Li, Weng, Jian-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838045/
https://www.ncbi.nlm.nih.gov/pubmed/35163992
http://dx.doi.org/10.3390/molecules27030726

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