Enantiotropy of Simvastatin as a Result of Weakened Interactions in the Crystal Lattice: Entropy-Driven Double Transitions and the Transient Modulated Phase as Seen by Solid-State NMR Spectroscopy

In crystalline molecular solids, in the absence of strong intermolecular interactions, entropy-driven processes play a key role in the formation of dynamically modulated transient phases. Specifically, in crystalline simvastatin, the observed fully reversible enantiotropic behavior is associated wit...

Descripción completa

Detalles Bibliográficos
Autores principales: Brus, Jiri, Czernek, Jiri, Urbanova, Martina, Červinka, Ctirad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838109/
https://www.ncbi.nlm.nih.gov/pubmed/35163943
http://dx.doi.org/10.3390/molecules27030679

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838109/
https://www.ncbi.nlm.nih.gov/pubmed/35163943
http://dx.doi.org/10.3390/molecules27030679

Ejemplares similares