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Coumarin-Resveratrol-Inspired Hybrids as Monoamine Oxidase B Inhibitors: 3-Phenylcoumarin versus trans-6-Styrylcoumarin
Monoamine oxidases (MAOs) are attractive targets in drug design. The inhibition of one of the isoforms (A or B) is responsible for modulating the levels of different neurotransmitters in the central nervous system, as well as the production of reactive oxygen species. Molecules that act selectively...
Autores principales: | Mellado, Marco, González, César, Mella, Jaime, Aguilar, Luis F., Celik, Ismail, Borges, Fernanda, Uriarte, Eugenio, Delogu, Giovanna, Viña, Dolores, Matos, Maria J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838197/ https://www.ncbi.nlm.nih.gov/pubmed/35164192 http://dx.doi.org/10.3390/molecules27030928 |
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