Disrupting the MAD2L2-Rev1 Complex Enhances Cell Death upon DNA Damage

DNA-damaging chemotherapy agents such as cisplatin have been the first line of treatment for cancer for decades. While chemotherapy can be very effective, its long-term success is often reduced by intrinsic and acquired drug resistance, accompanied by chemotherapy-resistant secondary malignancies. A...

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Detalles Bibliográficos
Autores principales: Pernicone, Nomi, Elias, Maria, Onn, Itay, Tobi, Dror, Listovsky, Tamar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838411/
https://www.ncbi.nlm.nih.gov/pubmed/35163901
http://dx.doi.org/10.3390/molecules27030636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838411/
https://www.ncbi.nlm.nih.gov/pubmed/35163901
http://dx.doi.org/10.3390/molecules27030636

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