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Disrupting the MAD2L2-Rev1 Complex Enhances Cell Death upon DNA Damage
DNA-damaging chemotherapy agents such as cisplatin have been the first line of treatment for cancer for decades. While chemotherapy can be very effective, its long-term success is often reduced by intrinsic and acquired drug resistance, accompanied by chemotherapy-resistant secondary malignancies. A...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838411/ https://www.ncbi.nlm.nih.gov/pubmed/35163901 http://dx.doi.org/10.3390/molecules27030636 |