Discovery of Novel Pleuromutilin Derivatives as Potent Antibacterial Agents for the Treatment of MRSA Infection

A series of novel pleuromutilin derivatives containing nitrogen groups on the side chain of C14 were synthesized under mild conditions. Most of the synthesized derivatives displayed potent antibacterial activities. Compound 9 was found to be the most active antibacterial derivative against MRSA (MIC...

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Detalles Bibliográficos
Autores principales: Fang, Han-Qing, Zeng, Jie, Wang, Shou-Kai, Wang, Xiao, Chen, Fang, Li, Bo, Liu, Jie, Jin, Zhen, Liu, Ya-Hong, Tang, You-Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838415/
https://www.ncbi.nlm.nih.gov/pubmed/35164203
http://dx.doi.org/10.3390/molecules27030931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838415/
https://www.ncbi.nlm.nih.gov/pubmed/35164203
http://dx.doi.org/10.3390/molecules27030931

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