Cargando…
Root Cultures, a Boon for the Production of Valuable Compounds: A Comparative Review
Medicinal plants are an inevitable source of pharmaceutical drugs and most of the world population depends on these plants for health benefits. The increasing global demand for bioactive compounds from medicinal plants has posed a great threat to their existence due to overexploitation. Adventitious...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838425/ https://www.ncbi.nlm.nih.gov/pubmed/35161423 http://dx.doi.org/10.3390/plants11030439 |
_version_ | 1784650124481265664 |
---|---|
author | Hussain, Masooma Jawad Abbas, Yawar Nazli, Naushaba Fatima, Sara Drouet, Samantha Hano, Christophe Abbasi, Bilal Haider |
author_facet | Hussain, Masooma Jawad Abbas, Yawar Nazli, Naushaba Fatima, Sara Drouet, Samantha Hano, Christophe Abbasi, Bilal Haider |
author_sort | Hussain, Masooma Jawad |
collection | PubMed |
description | Medicinal plants are an inevitable source of pharmaceutical drugs and most of the world population depends on these plants for health benefits. The increasing global demand for bioactive compounds from medicinal plants has posed a great threat to their existence due to overexploitation. Adventitious root and hairy root culture systems are an alternative approach to the conventional method for mass production of valuable compounds from medicinal plants owing to their rapid growth, biosynthetic and genetic stability. The main purpose of this review is to investigate the recent scientific research published worldwide on the application of adventitious and hairy root cultures to produce valuable compounds from medicinal plants. Furthermore, a comparison of adventitious root vs. hairy root cultures to produce valuable compounds has also been discussed. Various aspects such as medium composition, carbon source, pH, amount of macronutrients, optimization strategy, scale-up cultures, and use of biotic abiotic and nano-elicitors at various concentrations are the topic of discussion in this review. Several studies on adventitious and hairy root cultures of Polygonum multiflorum¸ Withania somnifera¸ Echinacea purpurea and Ajuga bracteosa have been discussed in detail which highlights the importance of elicitation strategies and bioreactor system, presenting commercial applications. |
format | Online Article Text |
id | pubmed-8838425 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-88384252022-02-13 Root Cultures, a Boon for the Production of Valuable Compounds: A Comparative Review Hussain, Masooma Jawad Abbas, Yawar Nazli, Naushaba Fatima, Sara Drouet, Samantha Hano, Christophe Abbasi, Bilal Haider Plants (Basel) Review Medicinal plants are an inevitable source of pharmaceutical drugs and most of the world population depends on these plants for health benefits. The increasing global demand for bioactive compounds from medicinal plants has posed a great threat to their existence due to overexploitation. Adventitious root and hairy root culture systems are an alternative approach to the conventional method for mass production of valuable compounds from medicinal plants owing to their rapid growth, biosynthetic and genetic stability. The main purpose of this review is to investigate the recent scientific research published worldwide on the application of adventitious and hairy root cultures to produce valuable compounds from medicinal plants. Furthermore, a comparison of adventitious root vs. hairy root cultures to produce valuable compounds has also been discussed. Various aspects such as medium composition, carbon source, pH, amount of macronutrients, optimization strategy, scale-up cultures, and use of biotic abiotic and nano-elicitors at various concentrations are the topic of discussion in this review. Several studies on adventitious and hairy root cultures of Polygonum multiflorum¸ Withania somnifera¸ Echinacea purpurea and Ajuga bracteosa have been discussed in detail which highlights the importance of elicitation strategies and bioreactor system, presenting commercial applications. MDPI 2022-02-05 /pmc/articles/PMC8838425/ /pubmed/35161423 http://dx.doi.org/10.3390/plants11030439 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Hussain, Masooma Jawad Abbas, Yawar Nazli, Naushaba Fatima, Sara Drouet, Samantha Hano, Christophe Abbasi, Bilal Haider Root Cultures, a Boon for the Production of Valuable Compounds: A Comparative Review |
title | Root Cultures, a Boon for the Production of Valuable Compounds: A Comparative Review |
title_full | Root Cultures, a Boon for the Production of Valuable Compounds: A Comparative Review |
title_fullStr | Root Cultures, a Boon for the Production of Valuable Compounds: A Comparative Review |
title_full_unstemmed | Root Cultures, a Boon for the Production of Valuable Compounds: A Comparative Review |
title_short | Root Cultures, a Boon for the Production of Valuable Compounds: A Comparative Review |
title_sort | root cultures, a boon for the production of valuable compounds: a comparative review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838425/ https://www.ncbi.nlm.nih.gov/pubmed/35161423 http://dx.doi.org/10.3390/plants11030439 |
work_keys_str_mv | AT hussainmasoomajawad rootculturesaboonfortheproductionofvaluablecompoundsacomparativereview AT abbasyawar rootculturesaboonfortheproductionofvaluablecompoundsacomparativereview AT nazlinaushaba rootculturesaboonfortheproductionofvaluablecompoundsacomparativereview AT fatimasara rootculturesaboonfortheproductionofvaluablecompoundsacomparativereview AT drouetsamantha rootculturesaboonfortheproductionofvaluablecompoundsacomparativereview AT hanochristophe rootculturesaboonfortheproductionofvaluablecompoundsacomparativereview AT abbasibilalhaider rootculturesaboonfortheproductionofvaluablecompoundsacomparativereview |