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New Imatinib Derivatives with Antiproliferative Activity against A549 and K562 Cancer Cells
Tyrosine kinase enzymes are among the primary molecular targets for the treatment of some human neoplasms, such as those in lung cancer and chronic myeloid leukemia. Mutations in the enzyme domain can cause resistance and new inhibitors capable of circumventing these mutations are highly desired. Th...
Autores principales: | Oliveira, Andressa, Moura, Stefany, Pimentel, Luiz, Neto, João, Dantas, Rafael, Silva-Jr, Floriano, Bastos, Monica, Boechat, Nubia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838532/ https://www.ncbi.nlm.nih.gov/pubmed/35164014 http://dx.doi.org/10.3390/molecules27030750 |
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