Unprecedented Epimerization of an Azithromycin Analogue: Synthesis, Structure and Biological Activity of 2′-Dehydroxy-5″-Epi-Azithromycin

Certain macrolide antibiotics, azithromycin included, possess anti-inflammatory properties that are considered fundamental for their efficacy in the treatment of chronic inflammatory diseases, such as diffuse pan-bronchiolitis and cystic fibrosis. In this study, we disclose a novel azithromycin anal...

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Detalles Bibliográficos
Autores principales: Kragol, Goran, Steadman, Victoria A., Marušić Ištuk, Zorica, Čikoš, Ana, Bosnar, Martina, Jelić, Dubravko, Ergović, Gabrijela, Trzun, Marija, Bošnjak, Berislav, Bokulić, Ana, Padovan, Jasna, Glojnarić, Ines, Eraković Haber, Vesna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838534/
https://www.ncbi.nlm.nih.gov/pubmed/35164298
http://dx.doi.org/10.3390/molecules27031034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838534/
https://www.ncbi.nlm.nih.gov/pubmed/35164298
http://dx.doi.org/10.3390/molecules27031034

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