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A High-Performance Deep Neural Network Model for BI-RADS Classification of Screening Mammography
Globally, the incidence rate for breast cancer ranks first. Treatment for early-stage breast cancer is highly cost effective. Five-year survival rate for stage 0–2 breast cancer exceeds 90%. Screening mammography has been acknowledged as the most reliable way to diagnose breast cancer at an early st...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838754/ https://www.ncbi.nlm.nih.gov/pubmed/35161903 http://dx.doi.org/10.3390/s22031160 |
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author | Tsai, Kuen-Jang Chou, Mei-Chun Li, Hao-Ming Liu, Shin-Tso Hsu, Jung-Hsiu Yeh, Wei-Cheng Hung, Chao-Ming Yeh, Cheng-Yu Hwang, Shaw-Hwa |
author_facet | Tsai, Kuen-Jang Chou, Mei-Chun Li, Hao-Ming Liu, Shin-Tso Hsu, Jung-Hsiu Yeh, Wei-Cheng Hung, Chao-Ming Yeh, Cheng-Yu Hwang, Shaw-Hwa |
author_sort | Tsai, Kuen-Jang |
collection | PubMed |
description | Globally, the incidence rate for breast cancer ranks first. Treatment for early-stage breast cancer is highly cost effective. Five-year survival rate for stage 0–2 breast cancer exceeds 90%. Screening mammography has been acknowledged as the most reliable way to diagnose breast cancer at an early stage. Taiwan government has been urging women without any symptoms, aged between 45 and 69, to have a screening mammogram bi-yearly. This brings about a large workload for radiologists. In light of this, this paper presents a deep neural network (DNN)-based model as an efficient and reliable tool to assist radiologists with mammographic interpretation. For the first time in the literature, mammograms are completely classified into BI-RADS categories 0, 1, 2, 3, 4A, 4B, 4C and 5. The proposed model was trained using block-based images segmented from a mammogram dataset of our own. A block-based image was applied to the model as an input, and a BI-RADS category was predicted as an output. At the end of this paper, the outperformance of this work is demonstrated by an overall accuracy of 94.22%, an average sensitivity of 95.31%, an average specificity of 99.15% and an area under curve (AUC) of 0.9723. When applied to breast cancer screening for Asian women who are more likely to have dense breasts, this model is expected to give a higher accuracy than others in the literature, since it was trained using mammograms taken from Taiwanese women. |
format | Online Article Text |
id | pubmed-8838754 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-88387542022-02-13 A High-Performance Deep Neural Network Model for BI-RADS Classification of Screening Mammography Tsai, Kuen-Jang Chou, Mei-Chun Li, Hao-Ming Liu, Shin-Tso Hsu, Jung-Hsiu Yeh, Wei-Cheng Hung, Chao-Ming Yeh, Cheng-Yu Hwang, Shaw-Hwa Sensors (Basel) Article Globally, the incidence rate for breast cancer ranks first. Treatment for early-stage breast cancer is highly cost effective. Five-year survival rate for stage 0–2 breast cancer exceeds 90%. Screening mammography has been acknowledged as the most reliable way to diagnose breast cancer at an early stage. Taiwan government has been urging women without any symptoms, aged between 45 and 69, to have a screening mammogram bi-yearly. This brings about a large workload for radiologists. In light of this, this paper presents a deep neural network (DNN)-based model as an efficient and reliable tool to assist radiologists with mammographic interpretation. For the first time in the literature, mammograms are completely classified into BI-RADS categories 0, 1, 2, 3, 4A, 4B, 4C and 5. The proposed model was trained using block-based images segmented from a mammogram dataset of our own. A block-based image was applied to the model as an input, and a BI-RADS category was predicted as an output. At the end of this paper, the outperformance of this work is demonstrated by an overall accuracy of 94.22%, an average sensitivity of 95.31%, an average specificity of 99.15% and an area under curve (AUC) of 0.9723. When applied to breast cancer screening for Asian women who are more likely to have dense breasts, this model is expected to give a higher accuracy than others in the literature, since it was trained using mammograms taken from Taiwanese women. MDPI 2022-02-03 /pmc/articles/PMC8838754/ /pubmed/35161903 http://dx.doi.org/10.3390/s22031160 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Tsai, Kuen-Jang Chou, Mei-Chun Li, Hao-Ming Liu, Shin-Tso Hsu, Jung-Hsiu Yeh, Wei-Cheng Hung, Chao-Ming Yeh, Cheng-Yu Hwang, Shaw-Hwa A High-Performance Deep Neural Network Model for BI-RADS Classification of Screening Mammography |
title | A High-Performance Deep Neural Network Model for BI-RADS Classification of Screening Mammography |
title_full | A High-Performance Deep Neural Network Model for BI-RADS Classification of Screening Mammography |
title_fullStr | A High-Performance Deep Neural Network Model for BI-RADS Classification of Screening Mammography |
title_full_unstemmed | A High-Performance Deep Neural Network Model for BI-RADS Classification of Screening Mammography |
title_short | A High-Performance Deep Neural Network Model for BI-RADS Classification of Screening Mammography |
title_sort | high-performance deep neural network model for bi-rads classification of screening mammography |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838754/ https://www.ncbi.nlm.nih.gov/pubmed/35161903 http://dx.doi.org/10.3390/s22031160 |
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