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Pentacyclic Triterpenoids Isolated from Celastraceae: A Focus in the (13)C-NMR Data

The Celastraceae family comprises about 96 genera and more than 1.350 species, occurring mainly in tropical and subtropical regions of the world. The species of this family stand out as important plant sources of triterpenes, both in terms of abundance and structural diversity. Triterpenoids found i...

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Detalles Bibliográficos
Autores principales: Camargo, Karen Caroline, de Aguilar, Mariana Guerra, Moraes, Acácio Raphael Aguiar, de Castro, Raquel Goes, Szczerbowski, Daiane, Miguel, Elizabeth Luciana Marinho, Oliveira, Leila Renan, Sousa, Grasiely Faria, Vidal, Diogo Montes, Duarte, Lucienir Pains
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838773/
https://www.ncbi.nlm.nih.gov/pubmed/35164224
http://dx.doi.org/10.3390/molecules27030959
Descripción
Sumario:The Celastraceae family comprises about 96 genera and more than 1.350 species, occurring mainly in tropical and subtropical regions of the world. The species of this family stand out as important plant sources of triterpenes, both in terms of abundance and structural diversity. Triterpenoids found in Celastraceae species display mainly lupane, ursane, oleanane, and friedelane skeletons, exhibiting a wide range of biological activities such as antiviral, antimicrobial, analgesic, anti-inflammatory, and cytotoxic against various tumor cell lines. This review aimed to document all triterpenes isolated from different botanical parts of species of the Celastraceae family covering 2001 to 2021. Furthermore, a compilation of their (13)C-NMR data was carried out to help characterize compounds in future investigations. A total of 504 pentacyclic triterpenes were compiled and distinguished as 29 aromatic, 50 dimers, 103 friedelanes, 89 lupanes, 102 oleananes, 22 quinonemethides, 88 ursanes and 21 classified as others.