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Pentacyclic Triterpenoids Isolated from Celastraceae: A Focus in the (13)C-NMR Data

The Celastraceae family comprises about 96 genera and more than 1.350 species, occurring mainly in tropical and subtropical regions of the world. The species of this family stand out as important plant sources of triterpenes, both in terms of abundance and structural diversity. Triterpenoids found i...

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Autores principales: Camargo, Karen Caroline, de Aguilar, Mariana Guerra, Moraes, Acácio Raphael Aguiar, de Castro, Raquel Goes, Szczerbowski, Daiane, Miguel, Elizabeth Luciana Marinho, Oliveira, Leila Renan, Sousa, Grasiely Faria, Vidal, Diogo Montes, Duarte, Lucienir Pains
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838773/
https://www.ncbi.nlm.nih.gov/pubmed/35164224
http://dx.doi.org/10.3390/molecules27030959
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author Camargo, Karen Caroline
de Aguilar, Mariana Guerra
Moraes, Acácio Raphael Aguiar
de Castro, Raquel Goes
Szczerbowski, Daiane
Miguel, Elizabeth Luciana Marinho
Oliveira, Leila Renan
Sousa, Grasiely Faria
Vidal, Diogo Montes
Duarte, Lucienir Pains
author_facet Camargo, Karen Caroline
de Aguilar, Mariana Guerra
Moraes, Acácio Raphael Aguiar
de Castro, Raquel Goes
Szczerbowski, Daiane
Miguel, Elizabeth Luciana Marinho
Oliveira, Leila Renan
Sousa, Grasiely Faria
Vidal, Diogo Montes
Duarte, Lucienir Pains
author_sort Camargo, Karen Caroline
collection PubMed
description The Celastraceae family comprises about 96 genera and more than 1.350 species, occurring mainly in tropical and subtropical regions of the world. The species of this family stand out as important plant sources of triterpenes, both in terms of abundance and structural diversity. Triterpenoids found in Celastraceae species display mainly lupane, ursane, oleanane, and friedelane skeletons, exhibiting a wide range of biological activities such as antiviral, antimicrobial, analgesic, anti-inflammatory, and cytotoxic against various tumor cell lines. This review aimed to document all triterpenes isolated from different botanical parts of species of the Celastraceae family covering 2001 to 2021. Furthermore, a compilation of their (13)C-NMR data was carried out to help characterize compounds in future investigations. A total of 504 pentacyclic triterpenes were compiled and distinguished as 29 aromatic, 50 dimers, 103 friedelanes, 89 lupanes, 102 oleananes, 22 quinonemethides, 88 ursanes and 21 classified as others.
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spelling pubmed-88387732022-02-13 Pentacyclic Triterpenoids Isolated from Celastraceae: A Focus in the (13)C-NMR Data Camargo, Karen Caroline de Aguilar, Mariana Guerra Moraes, Acácio Raphael Aguiar de Castro, Raquel Goes Szczerbowski, Daiane Miguel, Elizabeth Luciana Marinho Oliveira, Leila Renan Sousa, Grasiely Faria Vidal, Diogo Montes Duarte, Lucienir Pains Molecules Review The Celastraceae family comprises about 96 genera and more than 1.350 species, occurring mainly in tropical and subtropical regions of the world. The species of this family stand out as important plant sources of triterpenes, both in terms of abundance and structural diversity. Triterpenoids found in Celastraceae species display mainly lupane, ursane, oleanane, and friedelane skeletons, exhibiting a wide range of biological activities such as antiviral, antimicrobial, analgesic, anti-inflammatory, and cytotoxic against various tumor cell lines. This review aimed to document all triterpenes isolated from different botanical parts of species of the Celastraceae family covering 2001 to 2021. Furthermore, a compilation of their (13)C-NMR data was carried out to help characterize compounds in future investigations. A total of 504 pentacyclic triterpenes were compiled and distinguished as 29 aromatic, 50 dimers, 103 friedelanes, 89 lupanes, 102 oleananes, 22 quinonemethides, 88 ursanes and 21 classified as others. MDPI 2022-01-31 /pmc/articles/PMC8838773/ /pubmed/35164224 http://dx.doi.org/10.3390/molecules27030959 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Camargo, Karen Caroline
de Aguilar, Mariana Guerra
Moraes, Acácio Raphael Aguiar
de Castro, Raquel Goes
Szczerbowski, Daiane
Miguel, Elizabeth Luciana Marinho
Oliveira, Leila Renan
Sousa, Grasiely Faria
Vidal, Diogo Montes
Duarte, Lucienir Pains
Pentacyclic Triterpenoids Isolated from Celastraceae: A Focus in the (13)C-NMR Data
title Pentacyclic Triterpenoids Isolated from Celastraceae: A Focus in the (13)C-NMR Data
title_full Pentacyclic Triterpenoids Isolated from Celastraceae: A Focus in the (13)C-NMR Data
title_fullStr Pentacyclic Triterpenoids Isolated from Celastraceae: A Focus in the (13)C-NMR Data
title_full_unstemmed Pentacyclic Triterpenoids Isolated from Celastraceae: A Focus in the (13)C-NMR Data
title_short Pentacyclic Triterpenoids Isolated from Celastraceae: A Focus in the (13)C-NMR Data
title_sort pentacyclic triterpenoids isolated from celastraceae: a focus in the (13)c-nmr data
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838773/
https://www.ncbi.nlm.nih.gov/pubmed/35164224
http://dx.doi.org/10.3390/molecules27030959
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