Cargando…
Pentacyclic Triterpenoids Isolated from Celastraceae: A Focus in the (13)C-NMR Data
The Celastraceae family comprises about 96 genera and more than 1.350 species, occurring mainly in tropical and subtropical regions of the world. The species of this family stand out as important plant sources of triterpenes, both in terms of abundance and structural diversity. Triterpenoids found i...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838773/ https://www.ncbi.nlm.nih.gov/pubmed/35164224 http://dx.doi.org/10.3390/molecules27030959 |
_version_ | 1784650207902826496 |
---|---|
author | Camargo, Karen Caroline de Aguilar, Mariana Guerra Moraes, Acácio Raphael Aguiar de Castro, Raquel Goes Szczerbowski, Daiane Miguel, Elizabeth Luciana Marinho Oliveira, Leila Renan Sousa, Grasiely Faria Vidal, Diogo Montes Duarte, Lucienir Pains |
author_facet | Camargo, Karen Caroline de Aguilar, Mariana Guerra Moraes, Acácio Raphael Aguiar de Castro, Raquel Goes Szczerbowski, Daiane Miguel, Elizabeth Luciana Marinho Oliveira, Leila Renan Sousa, Grasiely Faria Vidal, Diogo Montes Duarte, Lucienir Pains |
author_sort | Camargo, Karen Caroline |
collection | PubMed |
description | The Celastraceae family comprises about 96 genera and more than 1.350 species, occurring mainly in tropical and subtropical regions of the world. The species of this family stand out as important plant sources of triterpenes, both in terms of abundance and structural diversity. Triterpenoids found in Celastraceae species display mainly lupane, ursane, oleanane, and friedelane skeletons, exhibiting a wide range of biological activities such as antiviral, antimicrobial, analgesic, anti-inflammatory, and cytotoxic against various tumor cell lines. This review aimed to document all triterpenes isolated from different botanical parts of species of the Celastraceae family covering 2001 to 2021. Furthermore, a compilation of their (13)C-NMR data was carried out to help characterize compounds in future investigations. A total of 504 pentacyclic triterpenes were compiled and distinguished as 29 aromatic, 50 dimers, 103 friedelanes, 89 lupanes, 102 oleananes, 22 quinonemethides, 88 ursanes and 21 classified as others. |
format | Online Article Text |
id | pubmed-8838773 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-88387732022-02-13 Pentacyclic Triterpenoids Isolated from Celastraceae: A Focus in the (13)C-NMR Data Camargo, Karen Caroline de Aguilar, Mariana Guerra Moraes, Acácio Raphael Aguiar de Castro, Raquel Goes Szczerbowski, Daiane Miguel, Elizabeth Luciana Marinho Oliveira, Leila Renan Sousa, Grasiely Faria Vidal, Diogo Montes Duarte, Lucienir Pains Molecules Review The Celastraceae family comprises about 96 genera and more than 1.350 species, occurring mainly in tropical and subtropical regions of the world. The species of this family stand out as important plant sources of triterpenes, both in terms of abundance and structural diversity. Triterpenoids found in Celastraceae species display mainly lupane, ursane, oleanane, and friedelane skeletons, exhibiting a wide range of biological activities such as antiviral, antimicrobial, analgesic, anti-inflammatory, and cytotoxic against various tumor cell lines. This review aimed to document all triterpenes isolated from different botanical parts of species of the Celastraceae family covering 2001 to 2021. Furthermore, a compilation of their (13)C-NMR data was carried out to help characterize compounds in future investigations. A total of 504 pentacyclic triterpenes were compiled and distinguished as 29 aromatic, 50 dimers, 103 friedelanes, 89 lupanes, 102 oleananes, 22 quinonemethides, 88 ursanes and 21 classified as others. MDPI 2022-01-31 /pmc/articles/PMC8838773/ /pubmed/35164224 http://dx.doi.org/10.3390/molecules27030959 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Camargo, Karen Caroline de Aguilar, Mariana Guerra Moraes, Acácio Raphael Aguiar de Castro, Raquel Goes Szczerbowski, Daiane Miguel, Elizabeth Luciana Marinho Oliveira, Leila Renan Sousa, Grasiely Faria Vidal, Diogo Montes Duarte, Lucienir Pains Pentacyclic Triterpenoids Isolated from Celastraceae: A Focus in the (13)C-NMR Data |
title | Pentacyclic Triterpenoids Isolated from Celastraceae: A Focus in the (13)C-NMR Data |
title_full | Pentacyclic Triterpenoids Isolated from Celastraceae: A Focus in the (13)C-NMR Data |
title_fullStr | Pentacyclic Triterpenoids Isolated from Celastraceae: A Focus in the (13)C-NMR Data |
title_full_unstemmed | Pentacyclic Triterpenoids Isolated from Celastraceae: A Focus in the (13)C-NMR Data |
title_short | Pentacyclic Triterpenoids Isolated from Celastraceae: A Focus in the (13)C-NMR Data |
title_sort | pentacyclic triterpenoids isolated from celastraceae: a focus in the (13)c-nmr data |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838773/ https://www.ncbi.nlm.nih.gov/pubmed/35164224 http://dx.doi.org/10.3390/molecules27030959 |
work_keys_str_mv | AT camargokarencaroline pentacyclictriterpenoidsisolatedfromcelastraceaeafocusinthe13cnmrdata AT deaguilarmarianaguerra pentacyclictriterpenoidsisolatedfromcelastraceaeafocusinthe13cnmrdata AT moraesacacioraphaelaguiar pentacyclictriterpenoidsisolatedfromcelastraceaeafocusinthe13cnmrdata AT decastroraquelgoes pentacyclictriterpenoidsisolatedfromcelastraceaeafocusinthe13cnmrdata AT szczerbowskidaiane pentacyclictriterpenoidsisolatedfromcelastraceaeafocusinthe13cnmrdata AT miguelelizabethlucianamarinho pentacyclictriterpenoidsisolatedfromcelastraceaeafocusinthe13cnmrdata AT oliveiraleilarenan pentacyclictriterpenoidsisolatedfromcelastraceaeafocusinthe13cnmrdata AT sousagrasielyfaria pentacyclictriterpenoidsisolatedfromcelastraceaeafocusinthe13cnmrdata AT vidaldiogomontes pentacyclictriterpenoidsisolatedfromcelastraceaeafocusinthe13cnmrdata AT duartelucienirpains pentacyclictriterpenoidsisolatedfromcelastraceaeafocusinthe13cnmrdata |