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The Antiproliferative and Apoptotic Effects of a Novel Quinazoline Carrying Substituted-Sulfonamides: In Vitro and Molecular Docking Study

In order to investigate for a new effective and safe anticancer drug, we synthesized a novel series of quinazoline containing biologically active substituted-sulfonamide moiety at 3- position 4a–n. The structure of the newly prepared compounds was proved by microanalysis, IR, (1)H-NMR, (13)C-NMR and...

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Detalles Bibliográficos
Autores principales: Alqahtani, Ali S., Ghorab, Mostafa M., Nasr, Fahd A., Ahmed, Mohammad Z., Al-Mishari, Abdullah A., Attia, Sabry M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838787/
https://www.ncbi.nlm.nih.gov/pubmed/35164248
http://dx.doi.org/10.3390/molecules27030981