Cargando…

Trifluoroethanol Promoted Castagnoli–Cushman Cycloadditions of Imines with Homophthalic Anhydride

Lactams are essential compounds in medicinal chemistry and key intermediates in the synthesis of natural products. The Castagnoli–Cushman reaction (CCR) of homophthalic anhydride with imines is an exciting method for accessing cyclic densely substituted lactam products. Most CCRs need to be catalyze...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bayles, Thibault, Guillou, Catherine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8839191/ https://www.ncbi.nlm.nih.gov/pubmed/35164109 http://dx.doi.org/10.3390/molecules27030844

Ejemplares similares

N-Methylimidazole Promotes the Reaction of Homophthalic Anhydride with Imines
por: Liu, Jian, et al.
Publicado: (2014)

The Castagnoli–Cushman Reaction
por: Ramiro, José Luis, et al.
Publicado: (2023)

The Use of Aryl-Substituted Homophthalic Anhydrides in the Castagnoli–Cushman Reaction Provides Access to Novel Tetrahydroisoquinolone Carboxylic Acid Bearing an All-Carbon Quaternary Stereogenic Center
por: Moshnenko, Nazar, et al.
Publicado: (2022)

Fluoral Hydrate: A Perspective Substrate for the Castagnoli–Cushman Reaction
por: Adamovskyi, Mykhailo I., et al.
Publicado: (2020)

Two Annulated Azaheterocyclic Cores Readily Available from a Single Tetrahydroisoquinolonic Castagnoli–Cushman Precursor
por: Karchuganova, Elizaveta, et al.
Publicado: (2020)

One-step route to tricyclic fused 1,2,3,4-tetrahydroisoquinoline systems via the Castagnoli–Cushman protocol
por: Pashev, Aleksandar, et al.
Publicado: (2020)

Modular synthesis and transition metal-free alkynylation/alkenylation of Castagnoli–Cushman-derived N,O- and N,S-heterocyclic vinyl chlorides
por: Beng, Timothy K., et al.
Publicado: (2020)

One-Pot Sequence of Staudinger/aza-Wittig/Castagnoli–Cushman Reactions Provides Facile Access to Novel Natural-like Polycyclic Ring Systems
por: Lebedev, Rodion, et al.
Publicado: (2022)

Extending the Scope of the New Variant of the Castagnoli–Cushman Cyclocondensation onto o-Methyl Benzoic Acids Bearing Various Electron-Withdrawing Groups in the α-Position
por: Guranova, Natalia, et al.
Publicado: (2022)

Three-component Castagnoli-Cushman reaction with ammonium acetate delivers 2-unsubstituted isoquinol-1-ones as potent inhibitors of poly(ADP-ribose) polymerase (PARP)
por: Safrygin, Alexander, et al.
Publicado: (2021)

Stereoselective Lewis base catalyzed formal 1,3-dipolar cycloaddition of azomethine imines with mixed anhydrides
por: Hesping, Lena, et al.
Publicado: (2015)

Extraction of Teeth, by Dr. Cushman
Publicado: (1851)

Dispirooxindole-β-Lactams: Synthesis via Staudinger Ketene-Imine Cycloaddition and Biological Evaluation
por: Filatov, Vadim E., et al.
Publicado: (2022)

Experimental Validation of the Role of Trifluoroethanol as a Nanocrowder
por: Culik, Robert M., et al.
Publicado: (2014)

Heterogeneous Preferential Solvation of Water and Trifluoroethanol in Homologous Lysozymes
por: Arthur, Evan J., et al.
Publicado: (2014)

Letter from Dr. C. T. Cushman, to the Baltimore Editor
por: Cushman, C. T.
Publicado: (1850)

Introducing a sulfone-embedded anhydride to the anhydride-imine reaction for the modular synthesis of N-heterocyclic sulfones bearing vicinal stereocenters
por: Beng, Timothy K., et al.
Publicado: (2023)

Diastereoselective Synthesis of γ- and δ-Lactams from Imines and Sulfone-Substituted Anhydrides
por: Sorto, Nohemy A., et al.
Publicado: (2014)

Crystal structure of l-leucyl-l-isoleucine 2,2,2-trifluoroethanol monosolvate
por: Görbitz, Carl Henrik
Publicado: (2016)

Cycloaddition of cyclobutenone and azomethine imine enabled by chiral isothiourea organic catalysts
por: Li, Bao-Sheng, et al.
Publicado: (2015)

Nicotinamide–2,2,2-trifluoroethanol (2/1)
por: Bardin, Julie, et al.
Publicado: (2009)

Letter from C. T. Cushman, M. D., to the Baltimore Editor
por: Cushman, C. T.
Publicado: (1849)

Synthesis of Non-Racemic Pyrazolines and Pyrazolidines by [3+2] Cycloadditions of Azomethine Imines
por: Požgan, Franc, et al.
Publicado: (2017)

An (R)‐Imine Reductase Biocatalyst for the Asymmetric Reduction of Cyclic Imines
por: Hussain, Shahed, et al.
Publicado: (2015)

Alkyl Formates as Transfer Hydroalkylation Reagents and Their Use in the Catalytic Conversion of Imines to Alkylamines
por: Crochet, Etienne, et al.
Publicado: (2022)

Thermodynamic Consistency of the Cushman Method of Computing the Configurational Entropy of a Landscape Lattice
por: Cushman, Samuel A.
Publicado: (2021)

Protein Modification by Strain-Promoted Alkyne–Nitrone Cycloaddition**
por: Ning, Xinghai, et al.
Publicado: (2010)

Catalytic Activation of Imines by Chalcogen Bond Donors in a Povarov [4+2] Cycloaddition Reaction
por: Steinke, Tim, et al.
Publicado: (2022)

Regioselective Cycloaddition of Nitrile Imines to 5-Methylidene-3-phenyl-hydantoin: Synthesis and DFT Calculations
por: Filkina, Maria E., et al.
Publicado: (2023)

Trifluoroethanol Modulates Amyloid Formation by the All α-Helical URN1 FF Domain
por: Marinelli, Patrizia, et al.
Publicado: (2013)

Structural Analysis and Aggregation Propensity of Pyroglutamate Aβ(3-40) in Aqueous Trifluoroethanol
por: Dammers, Christina, et al.
Publicado: (2015)

Recovery of bioactive protein from bacterial inclusion bodies using trifluoroethanol as solubilization agent
por: Upadhyay, Vaibhav, et al.
Publicado: (2016)

Chemoselectivity of Tertiary Azides in Strain‐Promoted Alkyne‐Azide Cycloadditions
por: Svatunek, Dennis, et al.
Publicado: (2018)

Asymmetric Synthesis of Bicyclic Pyrazolidinones through Alkaloid‐Catalyzed [3+2]‐Cycloadditions of Ketenes and Azomethine Imines
por: Mondal, Mukulesh, et al.
Publicado: (2022)

A Molecular Electron Density Theory Study of the Reactivity of Azomethine Imine in [3+2] Cycloaddition Reactions
por: Domingo, Luis R., et al.
Publicado: (2017)

In(OTf)(3)-catalyzed reorganization/cycloaddition of two imine units and subsequent modular assembly of acridinium photocatalysts
por: Nan, Jiang, et al.
Publicado: (2023)

Transformation of Imine Cages into Hydrocarbon Cages
por: Schick, Tobias H. G., et al.
Publicado: (2019)

[3 + 2] Cycloadditions of Tertiary Amine N-Oxides and Silyl Imines as an Innovative Route to 1,2-Diamines
por: Hejnosz, Sarah L., et al.
Publicado: (2023)

(3+2)-Cycloadditions of Levoglucosenone (LGO) with Fluorinated Nitrile Imines Derived from Trifluoroacetonitrile: An Experimental and Computational Study †
por: Mlostoń, Grzegorz, et al.
Publicado: (2023)

Imine Reduction with Me(2)S-BH(3)
por: Kamal, Mohammad M., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_r870cmoaa3mtgbltgom7q9s9t9