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Identification of Inhibitory Activities of Dietary Flavonoids against URAT1, a Renal Urate Re-Absorber: In Vitro Screening and Fractional Approach Focused on Rooibos Leaves
Hyperuricemia, a lifestyle-related disease characterized by elevated serum urate levels, is the main risk factor for gout; therefore, the serum urate-lowering effects of human diets or dietary ingredients have attracted widespread interest. As Urate transporter 1 (URAT1) governs most urate reabsorpt...
Autores principales: | Toyoda, Yu, Takada, Tappei, Saito, Hiroki, Hirata, Hiroshi, Ota-Kontani, Ami, Tsuchiya, Youichi, Suzuki, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8839210/ https://www.ncbi.nlm.nih.gov/pubmed/35276934 http://dx.doi.org/10.3390/nu14030575 |
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